Evidence map›Paper›PMID 41362759›Full record

ArticleiScience2025

Deciphering mechanisms leading to preterm birth through post-GWAS integration of multi-omics data.

Esha Bhattacharjee, Ramachandran Thiruvengadam, Divyank Varshney, Jagyashila Das, Ayushi, Rishika Maji, Piyali Mondal, Supratim Ghosh, Pragya Tailor, GARBH-Ini Study Team and 5 more

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Esha BhattacharjeeBiotechnology Research and Innovation Council - National Institute of Biomedical Genomics (BRIC-NIBMG), PO: NSS, Kalyani, West Bengal, India.
Ramachandran ThiruvengadamBiotechnology Research and Innovation Council - Translational Health Science and Technology Institute (BRIC-THSTI), 3 Milestone, Faridabad-Gurugram Expressway, Faridabad, Haryana, India.
Divyank VarshneyBiotechnology Research and Innovation Council - National Institute of Biomedical Genomics (BRIC-NIBMG), PO: NSS, Kalyani, West Bengal, India.
Jagyashila DasBiotechnology Research and Innovation Council - National Institute of Biomedical Genomics (BRIC-NIBMG), PO: NSS, Kalyani, West Bengal, India.
AyushiBiotechnology Research and Innovation Council - Translational Health Science and Technology Institute (BRIC-THSTI), 3 Milestone, Faridabad-Gurugram Expressway, Faridabad, Haryana, India.
Rishika MajiBiotechnology Research and Innovation Council - National Institute of Biomedical Genomics (BRIC-NIBMG), PO: NSS, Kalyani, West Bengal, India.
Piyali MondalBiotechnology Research and Innovation Council - National Institute of Biomedical Genomics (BRIC-NIBMG), PO: NSS, Kalyani, West Bengal, India.
Supratim GhoshBiotechnology Research and Innovation Council - National Institute of Biomedical Genomics (BRIC-NIBMG), PO: NSS, Kalyani, West Bengal, India.
Pragya TailorBiotechnology Research and Innovation Council - Translational Health Science and Technology Institute (BRIC-THSTI), 3 Milestone, Faridabad-Gurugram Expressway, Faridabad, Haryana, India.
GARBH-Ini Study Team
Uma Chandra Mouli NatchuBiotechnology Research and Innovation Council - Translational Health Science and Technology Institute (BRIC-THSTI), 3 Milestone, Faridabad-Gurugram Expressway, Faridabad, Haryana, India.
Nitya WadhwaBiotechnology Research and Innovation Council - Translational Health Science and Technology Institute (BRIC-THSTI), 3 Milestone, Faridabad-Gurugram Expressway, Faridabad, Haryana, India.
Pallavi KshetrapalBiotechnology Research and Innovation Council - Translational Health Science and Technology Institute (BRIC-THSTI), 3 Milestone, Faridabad-Gurugram Expressway, Faridabad, Haryana, India.
Shinjini BhatnagarBiotechnology Research and Innovation Council - Translational Health Science and Technology Institute (BRIC-THSTI), 3 Milestone, Faridabad-Gurugram Expressway, Faridabad, Haryana, India.
Arindam MaitraBiotechnology Research and Innovation Council - National Institute of Biomedical Genomics (BRIC-NIBMG), PO: NSS, Kalyani, West Bengal, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preterm birth (birth before 37 weeks) is a major cause of neonatal mortality and is linked to various health adversities in childhood and adult life. This study investigates the genetic factors contributing to spontaneous preterm birth (sPTB) in an Indian cohort. We conducted genome-wide association study of sPTB in GARBH-Ini cohort and identified 40 significantly associated SNPs, of which rs57480735 crossed genome-wide significance (

Indexed as

clinical geneticsomicswomen's health

Identifiers

PMID41362759
PMCPMC12682273

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.