ArticleOne health (Amsterdam, Netherlands)2025
LFD implementation uncovers hidden rabies burden: Pre- and post-implementation analysis and comparison with non-implementation sites in the Philippines.
Article in One health (Amsterdam, Netherlands), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Despite accumulating evidence supporting lateral flow devices (LFDs) in rabies diagnosis, their impacts of decentralizing diagnostic capacity on surveillance in endemic settings have not been systematically evaluated. Methods: We established low-resource decentralized rabies diagnostic laboratories in a target area of the Philippines, where rabies testing was previously unavailable, and evaluated both the diagnostic performance of LFD and their impacts on surveillance. Results: Using DFAT (direct fluorescent antibody test) as reference, LFDs performed at the decentralized laboratories showed a sensitivity of 97.0 % and a specificity of 98.2 %. After implementation, the monthly number of confirmed animal rabies cases in the target area increased from 2.09 to 8.65 cases, representing a 4.14-fold increase ( Conclusion: LFD-based decentralization markedly improved case detection and enabled critical outbreak responses at the local level, demonstrating its value for rabies control in endemic settings though sustained One Health approach remains a challenge following the detection of rabid animals using LFD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.