Evidence map›Paper›PMID 41362549›Full record

ReviewCureus2025

The Impact of Vitamin D Deficiency on Outcomes After Surgery for Adolescent Idiopathic Scoliosis: A Systematic Review.

Mariette Anto, Israa Elkashif, Sindhu Vithayathil, Maryam Walizada, Gowtham Siddi, Srirachana Reddy Gumireddy, Ann Kashmer Yu

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mariette AntoGeneral Medicine, King's Mill Hospital, Sutton-in-Ashfield, GBR.
Israa ElkashifPsychiatry, Royal College of Surgeons in Ireland, Dublin, IRL.
Sindhu VithayathilGeneral Medicine, American University of Antigua, Coolidge, ATG.
Maryam WalizadaInternal Medicine, Mary Washington Hospital, Fredericksburg, USA.
Gowtham SiddiMedicine, NRI Academy of Medical Sciences, Guntur, IND.
Srirachana Reddy GumireddyInternal Medicine, Apollo Institute of Medical Sciences and Research, Hyderabad, IND.
Ann Kashmer YuInternal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adolescent idiopathic scoliosis is a common spinal orthopedic condition that is associated with a high prevalence of vitamin D deficiency. Vitamin D is known to affect bone health, and we conducted a systematic review to assess the impact of vitamin D deficiency on patients diagnosed with adolescent idiopathic scoliosis who undergo surgery. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 checklist for our systematic review, utilizing various databases to conduct a thorough analysis of the current literature. We included specific search terms related to vitamin D deficiency and adolescent idiopathic scoliosis, and considered articles published between 2010 and 2025, focusing on papers with free full-text access. We used the PRISMA flowchart and initially identified 1,286 articles using the keywords for our search strategy across the databases. After removing duplicates, conducting title screening, assessing abstracts, and evaluating quality, we included 12 research papers in this review. Our review focused on the prevalence of vitamin D deficiency in adolescent idiopathic scoliosis patients and the impact of vitamin D deficiency on patients undergoing surgical management. This study was inconclusive in proving how significant the impact of vitamin D deficiency was in surgical adolescent idiopathic scoliosis patients, and we recommended conducting additional research to establish the importance of correcting vitamin D deficiency pre-operatively. However, considering that vitamin D has been linked to poorer surgical outcomes in most of the studies included in our review, we recommend routine screening for vitamin D in adolescent idiopathic scoliosis patients and its correction pre-operatively.

Indexed as

adolescent idiopathic scoliosis (ais)scoliosis surgeryspine surguryvitamin-dvitamin d deficiency

Identifiers

PMID41362549
PMCPMC12681963

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.