Evidence map›Paper›PMID 41362542›Full record

ArticleCureus2025

The Silent Obstruction: A Rare Complication of Non-steroidal Anti-inflammatory Drug (NSAID)-Induced Diaphragm Disease.

Edwin Mazhuppel Rechard, Ismaeel Al-Talib, Radhika Saigal, Lokesh Koumar Sivanandam

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Edwin Mazhuppel RechardInternal Medicine, The Royal Wolverhampton NHS Trust, Wolverhampton, GBR.
Ismaeel Al-TalibGastroenterology, Walsall Healthcare NHS Trust, Walsall, GBR.
Radhika SaigalInternal Medicine, Walsall Manor Hospital, Walsall, GBR.
Lokesh Koumar SivanandamInternal Medicine, Torbay and South Devon NHS Foundation Trust, Torquay, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diaphragm disease is a rare but significant complication of prolonged non-steroidal anti-inflammatory drug (NSAID) use, characterised by thin concentric mucosal diaphragms causing small bowel strictures.  This case report is on a 42-year-old woman with a chronic history of NSAID use, which led to the development of recurrent gastrointestinal symptoms, iron-deficiency anaemia, and subacute small bowel obstruction. Diaphragm disease was confirmed through histological analysis following surgical resection of the small bowel.  Patients who present with non-specific GI symptoms along with chronic NSAID use and unexplained obstruction should make us consider diaphragm disease within the differentials.

Indexed as

capsule retentiongastrointestinal stricturesmall bowel diaphragm diseasesmall-bowel obstructionsmall bowel resection

Identifiers

PMID41362542
PMCPMC12681954

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.