ReviewInfection and drug resistance2025
Antimicrobial and Anti-Infective Potential of Herbal Creams in Dermatology: Efficacy, Safety, and Challenges in Skin Infection Management.
Review in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Herbal creams are becoming increasingly popular in dermatology due to their potential to treat a variety of skin conditions, offering a natural, sustainable alternative to synthetic products. Derived from traditional medicine, these formulations contain plant-based bioactive compounds that provide anti-inflammatory, antimicrobial, antioxidant, and wound-healing properties. Common ingredients such as Aloe vera, tea tree oil, calendula, turmeric, chamomile, and liquorice are known to address skin issues including acne, eczema, psoriasis, and aging. Despite these advantages, safety concerns remain, as the natural origin of these products does not guarantee safety; some may cause allergic reactions or skin irritation, while impurities and contaminants pose additional risks. This underlines the importance of comprehensive safety evaluations. Furthermore, regulatory and quality control challenges make the market difficult to navigate, reinforcing the need for standardized production and rigorous testing to ensure consistency and safety. Although clinical trials and marketed formulations demonstrate the efficacy of herbal creams, variability in ingredient concentrations and a lack of regulation can affect outcomes. Future perspectives call for the integration of traditional herbal knowledge with modern scientific advancements to enhance the safety and effectiveness of these products. This review explores the antimicrobial and anti-infective efficacy of herbal creams, their skin penetration mechanisms, safety considerations, and regulatory challenges, emphasizing clinical trials and marketed formulations. By integrating traditional herbal knowledge with modern scientific advancements, herbal creams offer a promising approach to managing skin infections while minimizing antibiotic resistance, provided robust regulatory frameworks ensure product safety and consistency.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.