Evidence map›Paper›PMID 41362417›Full record

ArticleJGH open : an open access journal of gastroenterology and hepatology2025

Comparative Analysis of Gastric Epithelial Neoplasm of Fundic-Gland Mucosa Lineage: Histopathological Features of Background Gastric Mucosa.

Ryo Watanabe, Tomoyuki Yada, Takashi Oide, Miki Yoshinobu, Yugo Kawasaki, Masaaki Mino, Keita Odaka, Katsunori Sekine, Naomi Uemura

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JGH open : an open access journal of gastroenterology and hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ryo WatanabeDepartment of Gastroenterology and Hepatology National Kohnodai Medical Center, Japan Institute for Health Security Chiba Japan.ORCID https://orcid.org/0009-0006-9813-9386
Tomoyuki YadaDepartment of Gastroenterology and Hepatology National Kohnodai Medical Center, Japan Institute for Health Security Chiba Japan.ORCID https://orcid.org/0000-0002-7117-9509
Takashi OideDepartment of Pathology and Laboratory Medicine National Kohnodai Medical Center, Japan Institute for Health Security Chiba Japan.
Miki YoshinobuDepartment of Gastroenterology and Hepatology National Kohnodai Medical Center, Japan Institute for Health Security Chiba Japan.
Yugo KawasakiDepartment of Gastroenterology and Hepatology National Kohnodai Medical Center, Japan Institute for Health Security Chiba Japan.
Masaaki MinoDepartment of Gastroenterology and Hepatology National Kohnodai Medical Center, Japan Institute for Health Security Chiba Japan.
Keita OdakaDepartment of Gastroenterology and Hepatology National Kohnodai Medical Center, Japan Institute for Health Security Chiba Japan.
Katsunori SekineDepartment of Gastroenterology and Hepatology National Kohnodai Medical Center, Japan Institute for Health Security Chiba Japan.
Naomi UemuraDepartment of Gastroenterology and Hepatology National Kohnodai Medical Center, Japan Institute for Health Security Chiba Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Gastric epithelial neoplasm of fundic-gland mucosa lineage (GEN-FGML) has been increasingly recognized in recent years; however, few studies have investigated the histopathology of the background gastric mucosa surrounding the lesion. This study clarifies the histopathological features of the background gastric mucosa in GEN-FGML. Methods and Results: A retrospective analysis was conducted of 30 GEN-FGML lesions (28 patients) diagnosed at our institution between December 2012 and 2023, excluding cases of gastric adenocarcinoma of fundic-gland mucosa type. Patients were classified according to Conclusion: Oxyntic gland adenoma and gastric adenocarcinoma of fundic-gland type arise predominantly from mildly atrophic mucosa with preserved fundic glands in previously infected stomachs, and, albeit less frequently, from severely atrophic mucosa. During routine endoscopic examinations, careful observation of the fundic gland is warranted regardless of the presence of background mucosal atrophy.

Indexed as

Fundic glandsgastric adenocarcinomagastric mucosahelicobacter infectionsstomach neoplasms

Identifiers

PMID41362417
PMCPMC12682231

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.