ArticlePeerJ2025
Association between bone marrow adipose tissue, abdominal adipose tissue distribution, and volumetric bone mineral density in the Chinese adult population: a retrospective cohort study.
Article in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Association of intra-pancreatic fat deposition with bone marrow adiposity in young obese adults.Quantitative imaging in medicine and surgery · 2026Article
- Upper lumbar standardized subcutaneous fat index: a novel sex-independent indicator of bone mineral density and musculoskeletal fat infiltration.BMC musculoskeletal disorders · 2026Article
- Nomogram-Based Prediction Model for Suboptimal Weight Loss Outcomes After Metabolic Bariatric Surgery Using CT-Derived Body Composition Parameters: A Prospective Chinese Cohort Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Increasing studies have suggested that bone closely interacts with bone marrow adipose tissue (BMAT) and abdominal adipose tissue. However, this relationship remains debated. This study aimed to explore the association among BMAT, abdominal adipose tissue, and lumbar volumetric bone mineral density (vBMD). Methods: A total of 306 Chinese adult living liver transplant donors were enrolled in this cross-sectional study. vBMD and abdominal adipose tissue in terms of total adipose tissue (TAT), visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT), were derived using quantitative computed tomography (QCT). Chemical shift encoded magnetic resonance imaging (MRI) of the lumbar spine was performed, and proton density fat fraction (PDFF) maps were calculated. Correlation analysis and multiple linear regression were used to assess the associations among BMAT, abdominal adipose tissue distribution, and vBMD. Results: The mean age of the participants was 38.1 ± 9.5 years (range: 19-66 years). The vBMD was significantly negatively associated with age ( Conclusion: Our results indicated a negative association between BMAT and BMD. The association between abdominal adipose tissue distribution and BMD was dual; there was a positive association between SAT and BMD and a negative association between VAT and BMD. These findings suggest that the distribution of abdominal adipose tissue, particularly visceral adipose tissue accumulation, should be prioritized over total body weight in considerations of bone health.
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