Evidence map›Paper›PMID 41362354›Full record

ArticleBrain & spine2025

Lumboperitoneal shunting as a rescue strategy in the management of complex cranial wound conditions.

Christian Seemann, Jan Oros, Tobias Finger, Paul Kendlbacher, Sven König, Fatma Kilinç, Kristin Lucia, Christoph Hirche, Marcus Czabanka, Lina-Elisabeth Qasem and 1 more

Abstract read
In one paragraph

Article in Brain & spine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Christian SeemannDepartment of Neurosurgery, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Jan OrosDepartment of Neurosurgery, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Tobias FingerDepartment of Neurosurgery, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Paul KendlbacherDepartment of Neurosurgery, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Sven KönigDepartment of Neurosurgery, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Fatma KilinçDepartment of Neurosurgery, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Kristin LuciaDepartment of Neurosurgery, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Christoph HircheDepartment of Plastic, Hand and Reconstructive Microsurgery, BG Trauma Center Frankfurt am Main, Germany.
Marcus CzabankaDepartment of Neurosurgery, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Lina-Elisabeth QasemDepartment of Neurosurgery, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Vincent PrinzDepartment of Neurosurgery, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Complex cranial wound conditions (CCWC), particularly when associated with hydrocephalus and/or implant-related infections, pose a major challenge in neurosurgical complication management. In such cases, moving the shunt system from the cranial to the lumbar compartment appears to be a valuable salvage strategy. Research question: Can lumboperitoneal shunting (LPS) including differential pressure and gravitational valves serve as an effective rescue strategy in patients with different types of CCWC? Methods: We conducted a single-center retrospective study of 15 patients treated with LPS implantation for CCWC between March 2023 and August 2025. Clinical data were extracted from medical records, including patient demographics, CCWC type, surgical parameters, complications and outcomes. Results: The cohort included 8 female and 7 male patients, with a median age of 53 years (range, 25-87). CCWC secondary to CSF fistulas following tumor resection accounted for 9 cases, VPS-associated infection for 3 cases, and decompressive craniectomy for 3 cases. In 5 patients, wound healing was further impaired by prior radiation and chemotherapy. Median surgical time was 60 min (IQR, 47-82), and median hospitalization was 6 days (IQR, 3-15). Wound healing resolved after LPS implantation in all but one patient. Complications occurred in 2 patients, both related to overdrainage. Implant survival rate was 100 %. Conclusion: LPS implantation represents a valuable salvage strategy for patients with CCWC, particularly in the context of decompressive craniectomy, radiation-exposed tissue, or prior implant-associated infection. LPS promotes cranial wound healing while ensuring CSF diversion, with adjustable gravitational valves being essential especially in craniectomized patients.

Indexed as

Complication managementComplicationsHydrocephalusLumboperitoneal shuntVentriculoperitoneal shuntWound healing condition

Identifiers

PMID41362354
PMCPMC12682124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.