Evidence map›Paper›PMID 41361797›Full record

ArticleBMC cardiovascular disorders2025

The effect of the pericardial patching exclusion technique for left atrial appendage closure on postoperative reopening rate.

Qinpu Wang, Yijing Su, Jiajun Zhong, Jianan Li, Xinlei Ren, Junze Xuan, Weicong Huang, Jue Wang

Abstract readComparative Study
In one paragraph

Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Qinpu WangDepartment of Cardiac Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, P.R. China.
Yijing SuDepartment of Cardiac Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, P.R. China.
Jiajun ZhongDepartment of Cardiac Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, P.R. China.
Jianan LiDepartment of Cardiac Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, P.R. China.
Xinlei RenDepartment of Cardiac Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, P.R. China.
Junze XuanDepartment of Cardiac Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, P.R. China.
Weicong HuangDepartment of Cardiac Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, P.R. China.
Jue WangDepartment of Cardiac Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, P.R. China. drwangjue@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe left atrial appendage (LAA) is the primary source of cardiogenic embolism in atrial fibrillation patients. Traditional LAA closure methods have shown suboptimal clinical outcomes. In recent years, some surgeons have proposed employing a autologous pericardial patch for suturing the LAA.

methodsThis study included 104 patients undergoing mitral valve surgery with concomitant LAA closure at our center between January 2019 and December 2021. Two surgical methods for LAA closure were compared. A transesophageal echocardiogram performed 6 months after surgery was used to verify the success of left atrial appendage closure. Left atrial appendage closure failure was defined as reopening of the left atrial appendage or persistent blood flow into the left atrial appendage.

resultsAmong the 104 patients included (mean age: 65.0 ± 7.58 years, male: 52.50%), 7 patients were found to have a reopened left atrial appendage; 5 patients (5 of 32,15.6%) were in the suture closure group, and 2 patients (2 of 72,2.8%) were in the pericardial patch exclusion (PPE; defined as closure of the LAA orifice via sutured autologous pericardium) group (15.6% vs. 2.8%, P = 0.047).

conclusionsThe pericardial patch exclusion technique is a reliable technique for closing the left atrial appendage in patients with atrial fibrillation and can effectively reduce the possibility of reopening the left atrial appendage.

Indexed as

Atrial AppendageAtrial FibrillationCardiac Surgical ProceduresMitral ValvePericardiumSuture TechniquesAgedFemaleHumansLeft Atrial Appendage ClosureMaleMiddle AgedRecurrenceRetrospective StudiesRisk FactorsTime FactorsAtrial fibrillationLeft atrial appendage closurePericardial patch exclusion

Identifiers

PMID41361797
PMCPMC12683840

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.