Evidence map›Paper›PMID 41361681›Full record

ArticleJournal of cardiovascular electrophysiology2026

Tandem Approach for Transvenous Lead Extraction: Efficacy, Safety, and Operational Learning Curve.

Alessio Petrone, Zaki Akhtar, Christos Kontogiannis, Viral Sagar, Jaspal Singh Gill, Lisa W M Leung, Zia Zuberi, Manav Sohal, Mark M Gallagher

Abstract read
In one paragraph

Article in Journal of cardiovascular electrophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alessio PetroneCardiology Clinical Academic Group, City St George's University Hospital, NHS Foundation Trust, London, UK.ORCID 0009-0007-3267-4105
Zaki AkhtarCardiology Clinical Academic Group, City St George's University Hospital, NHS Foundation Trust, London, UK.ORCID 0000-0002-9365-8826
Christos KontogiannisCardiology Clinical Academic Group, City St George's University Hospital, NHS Foundation Trust, London, UK.ORCID 0000-0002-1967-2654
Viral SagarCardiology Clinical Academic Group, City St George's University Hospital, NHS Foundation Trust, London, UK.ORCID 0009-0006-2445-4754
Jaspal Singh GillCardiology Clinical Academic Group, City St George's University Hospital, NHS Foundation Trust, London, UK.ORCID 0000-0001-9246-5371
Lisa W M LeungCardiology Clinical Academic Group, City St George's University Hospital, NHS Foundation Trust, London, UK.ORCID 0000-0001-7485-6440
Zia ZuberiCardiology Clinical Academic Group, City St George's University Hospital, NHS Foundation Trust, London, UK.
Manav SohalCardiology Clinical Academic Group, City St George's University Hospital, NHS Foundation Trust, London, UK.ORCID 0000-0002-5771-5504
Mark M GallagherCardiology Clinical Academic Group, City St George's University Hospital, NHS Foundation Trust, London, UK.ORCID 0000-0002-6333-6420

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

BACKGROUND AND

aimsThe need for transvenous lead extraction (TLE) is rising due to increased cardiovascular device implantation and an aging population. While the superior access is standard, complex cases may benefit from the Tandem approach, combining femoral and superior access to improve efficacy and safety. This study evaluates outcomes and predictors associated with the Tandem approach as a primary strategy.

methodsA retrospective analysis was conducted on 148 patients who underwent Tandem TLE at a high-volume UK center between September 2020 and December 2024. Data on procedural success, complete lead removal, complications, and outcome predictors were collected. The Needle's eye snare (NES) learning curve was assessed via fluoroscopy time.

resultsMedian patient age was 72.4 years, with 42.6% considered high-risk (EROS 3). 319 leads were targeted, with 81.2% extracted via the Tandem approach. Clinical procedural success was 97.3%, and complete lead removal 93%. Use of Medtronic leads was the sole independent predictor of complete lead removal. Major complications occurred in 3.4% of cases, with no procedural mortality. BMI < 25 kg/m² and extraction of ≥ 3 leads were predictors of complications and 30-day mortality. NES proficiency improved significantly after 40 leads (p < 0.001), confirming a learning curve.

conclusionThe Tandem approach is a safe and effective primary strategy for complex TLE, particularly in cases involving passive fixation, shock, and long dwell times leads. However, widespread use may be limited by resource intensity, increased fluoroscopy exposure, and the need for experienced operators.

Indexed as

Catheterization, PeripheralDefibrillators, ImplantableDevice RemovalLearning CurvePacemaker, ArtificialAgedAged, 80 and overDevice Lead ExtractionFemaleHumansMaleMiddle AgedPuncturesRetrospective StudiesRisk AssessmentRisk FactorsNeedle's eye femoral snareoperational learning curvepredictors of efficacy and safetytandem approachtransvenous lead extraction

Identifiers

PMID41361681
PMCPMC13020655

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.