Evidence map›Paper›PMID 41361675›Full record

SynthesisThe veterinary quarterly2025

Epidemiology, clinical and pathological features and outcomes of listeriosis in ruminants: a systematic review and meta-analysis.

Inmaculada López-Almela, Chirag C Sheth, Jesús Gomis, Ángel Gómez-Martín, Marc Lecuit, Juan J Quereda

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in The veterinary quarterly, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Inmaculada López-AlmelaResearch Group Listeria: Biology and Infection. Departamento Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos, Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, Valencia, Spain.
Chirag C ShethFaculty of Health Sciences, Universidad Cardenal Herrera-CEU, CEU Universities, Valencia, Spain.
Jesús GomisResearch Group Microbiological Agents Associated with Animal Reproduction (ProVaginBIO). Departamento Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos, Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, Valencia, Spain.
Ángel Gómez-MartínResearch Group Microbiological Agents Associated with Animal Reproduction (ProVaginBIO). Departamento Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos, Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, Valencia, Spain.
Marc LecuitInstitut Pasteur, Université Paris Cité, Inserm U1117, Biology of Infection Unit, Paris, France.
Juan J QueredaResearch Group Listeria: Biology and Infection. Departamento Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos, Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, Valencia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We performed a systematic review and meta-analysis of the epidemiology, clinical and pathological features, outcomes, and therapy for listeriosis in ruminants. PubMed, Web of Science, and Scopus were searched with no publication date limits. A random-effects meta-analysis model was used to calculate the pooled effect size using morbidity and case fatality rate data. 63 and 38 studies met the inclusion criteria for the systematic review and meta-analysis, respectively. 56 out of 63 studies were published before 2016 when cgMLST was developed. A comprehensive analysis of historical data shows that the association of silage as a source of contamination in ruminants should be re-evaluated. The most common clinical presentation was encephalitis (64.8% of the animals, 1839/2837), followed by abortion (21.3% of the animals, 604/2837). The mortality rate was high despite treatment. Overall, the mean morbidity, case fatality rate, and abortion rate were 12.6%, 50.6%, and 12.8%, respectively. Meta-analysis of the subgroups revealed a Hedges' g value of -4.60 for the abortive form, indicating greater morbidity than mortality in this form. In contrast, the encephalitic form was characterized by a higher case fatality rate than morbidity (Hedges' g 9.46). Literature gaps exist since most reported outbreaks are from the twentieth century and only from a few countries. There is a lack of information on the current prevalence, consequences, and effectiveness of antimicrobial treatment of listeriosis in domestic ruminants. There is also an incomplete picture of the prevalence of

Indexed as

Cattle DiseasesGoat DiseasesListeriosisSheep DiseasesAbortion, VeterinaryAnimalsFemaleGoatsRuminantsSheepantibiotic treatmentcase fatality rateCattlegoatgross lesionshistopathologyinfectionmorbiditysheep

Identifiers

PMID41361675
PMCPMC12690773

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.