Evidence map›Paper›PMID 41361665›Full record

ReviewRadiologie (Heidelberg, Germany)2026

[Overview of CAR-T cell therapy : What the radiologist should know].

Mirjam Gerwing, Michel Eisenblätter

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Radiologie (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mirjam GerwingUniversitätsinstitut für Diagnostische und Interventionelle Radiologie, Med. Fakultät und Universitätsklinikum OWL, Klinikum Lippe, Universität Bielefeld, Röntgenstraße 18, 32756, Detmold, Deutschland. Mirjam.Gerwing@klinikum-lippe.de.
Michel EisenblätterUniversitätsinstitut für Diagnostische und Interventionelle Radiologie, Med. Fakultät und Universitätsklinikum OWL, Klinikum Lippe, Universität Bielefeld, Röntgenstraße 18, 32756, Detmold, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

clinical issueCAR-T cell therapy is complex and is now offered at a growing number of oncology centers in Germany. In addition to the initial CAR-T cell treatment, several advances and complementary therapies are available, which radiologists should be familiar with to properly evaluate treatment response and detect side effects early. STANDARD TREATMENT: In hemato-oncologic diseases, combinations of chemotherapy and targeted therapies are usually administered. TREATMENT INNOVATIONS: CAR-T-cell therapy combined with complementary immunotherapies. DIAGNOSTIC WORK-UP: For current indications, cross-sectional imaging-typically positron emission tomography/computed tomography-is used for staging and for evaluating therapy response. PERFORMANCE: The response rate is approximately 66.4% (25.5-90.9%). ACHIEVEMENTS: CAR-T cell therapy represents a new era in immunotherapy, and its recent advances mark a significant innovation in oncologic treatment. PRACTICAL RECOMMENDATIONS: Radiologists should understand the principles of CAR-T cell therapy in order to accurately assess treatment response and recognize early signs of potential side effects.

Indexed as

Immunotherapy, AdoptiveNeoplasmsReceptors, Chimeric AntigenHumansPositron Emission Tomography Computed TomographyReceptors, Chimeric AntigenHemato-oncologic diseasesImmunotherapyMechansim of actionSide effectsTherapy response

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.