Evidence map›Paper›PMID 41361654›Full record

SynthesisSpine deformity2026

Prevalence of cardiac abnormalities in patients with idiopathic scoliosis: a systematic review and meta-analysis.

Ahmed Baseem Ismail, Dima Hisham Fikry, Khaled A Elmenawi, Mohamed Moustafa, Ahmed Said Abdelwahed, Mohanad Abdelfattah, Sarah Ahmed Metwally, Mennatullah Shaker Arafat, Laial Al-Twisi, Aya Shebl Elnaggar and 1 more

Abstract readSystematic ReviewMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Spine deformity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ahmed Baseem IsmailDepartment of Neurosurgery, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Dima Hisham FikryDepartment of Cardiology, Ahmed Maher Teaching Hospital, Cairo, Egypt.ORCID http://orcid.org/0000-0002-2495-8403
Khaled A ElmenawiDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Mohamed MoustafaFaculty of Medicine, Cairo University, Cairo, Egypt.ORCID http://orcid.org/0000-0002-4182-3340
Ahmed Said AbdelwahedDepartment of Neurosurgery, Nasser Institute Hospital for Research and Treatment, Cairo, Egypt. aabdelwahed813@gmail.com.ORCID http://orcid.org/0009-0002-2948-3096
Mohanad AbdelfattahFaculty of Medicine, Cairo University, Cairo, Egypt.ORCID http://orcid.org/0000-0002-8598-2052
Sarah Ahmed MetwallyFaculty of Medicine, Cairo University, Cairo, Egypt.ORCID http://orcid.org/0009-0004-0310-7396
Mennatullah Shaker ArafatFaculty of Medicine, Cairo University, Cairo, Egypt.ORCID http://orcid.org/0000-0002-1094-1037
Laial Al-TwisiFaculty of Medicine, Cairo University, Cairo, Egypt.ORCID http://orcid.org/0009-0004-8205-4826
Aya Shebl ElnaggarFaculty of Medicine, Menoufia University, Shibin Al Kawm, Egypt.ORCID http://orcid.org/0009-0005-0959-337X
Khaled Ashraf MohamedGeneral Surgery Department, Cairo University, Giza, Egypt.ORCID http://orcid.org/0000-0002-0139-2873

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis systematic review and meta-analysis aim to investigate the prevalence of cardiac abnormalities in patients with idiopathic scoliosis.

methodsA systematic search on PubMed, Embase, Scopus, and Web of Science was conducted, covering studies published from their inception up to February 2024. Peer-reviewed studies that used echocardiograms to screen for cardiac abnormalities were included. Nine thousand five hundred fifty-four cases met the inclusion criteria and were included in the final data synthesis. A meta-analysis was performed to calculate the pooled prevalence of cardiac abnormalities and a 95% confidence interval (CI). Results were divided into subgroups to reveal the prevalence of each cardiac abnormality for further consideration.

results7.5% had cardiac abnormalities. Valvular diseases are the most common cardiac abnormalities. Tricuspid regurgitation (TR) is the most prevalent, accounting for 24.4% of cases. This is followed by mitral regurgitation (MR) at 17%, mitral valve prolapse (MVP) at 8%, aortic regurgitation (AR) at 3.8%, and pulmonary insufficiency at 1.9%. In addition, other valvular diseases collectively make up 22% of the findings. Congenital heart diseases (CHD) were also included in the results, with atrial septal defect (ASD) being the most prominent at 1.5%, followed by ventricular septal defect (VSD) at 1.4%, and other CHD comprising 2.5%. Pulmonary hypertension accounts for a substantial portion of the results, representing 16.8%. A dilated aortic root and pericardial effusion were observed in 2.4% and 0.9% of cases, respectively.

conclusionCardiovascular abnormalities are prevalent in patients with idiopathic scoliosis. This highlights the need for thorough cardiovascular screening of these patients before surgical intervention.

Indexed as

Heart Defects, CongenitalScoliosisEchocardiographyHumansPrevalenceCardiac abnormalitiesCardiac diseaseCardiac dysfunctionIdiopathic scoliosis

Identifiers

PMID41361654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.