Evidence map›Paper›PMID 41361411›Full record

ArticleBMC pregnancy and childbirth2025

Factors for successful vaginal delivery in twin pregnancies: a ten-year single-center retrospective study.

Hiroki Ito, Takashi Shibata, Toshio Shimokawa, Hiroki Kato, Shigeki Nishikawa, Satoshi Nakago

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Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Hiroki ItoDepartment of Obstetrics and Gynecology, Takatsuki General Hospital, Takatsuki, Japan.
Takashi ShibataDepartment of Obstetrics and Gynecology, Takatsuki General Hospital, Takatsuki, Japan. shibatanz@nifty.com.
Toshio ShimokawaDepartment of Medical Data Science, Graduate School of Medicine, Wakayama Medical University, Wakayama, Japan.
Hiroki KatoDepartment of Obstetrics and Gynecology, Takatsuki General Hospital, Takatsuki, Japan.
Shigeki NishikawaDepartment of Obstetrics and Gynecology, Takatsuki General Hospital, Takatsuki, Japan.
Satoshi NakagoDepartment of Obstetrics and Gynecology, Takatsuki General Hospital, Takatsuki, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhen certain conditions are met, a large randomized trial has suggested that for twin pregnancies, vaginal delivery does not increase adverse maternal or neonatal outcomes compared with cesarean section. However, the choice of the delivery mode is sometimes controversial, and policies can vary across different facilities. Identifying factors associated with successful vaginal delivery is important in reducing unnecessary cesarean sections.

methodsWe retrospectively analyzed 370 twin pregnancies delivered after 32 weeks of gestation at our hospital between April 2012 and March 2022, excluding monoamniotic monochorionic twins. Vaginal delivery was offered when the first twin was in cephalic presentation, the estimated fetal weight of each twin was at least 1500 g, and there were no other indications for cesarean section. We compared maternal and fetal factors between successful and failed attempts at vaginal delivery. Notably, we used multivariable logistic regression and the classification and regression tree (CART) method for statistical analyses.

resultsOf the 370 twin pregnancies, 133 women attempted vaginal delivery, and 115 (86.5%) achieved successful vaginal delivery of both twins. Multivariable analysis identified multiparity (adjusted odds ratio 15.29, 95% confidence interval 3.55-65.74; p < 0.001) and younger maternal age (adjusted odds ratio 0.84 per year, 95% confidence interval 0.73-0.96; p = 0.013) as independent predictors of successful vaginal delivery. CART analysis supported these findings, identifying parity as the primary discriminator. Among primiparas, maternal age ≤ 29 years emerged as a cutoff, with younger women having a higher probability of successful vaginal delivery. Univariable comparisons further supported this result.

conclusionsOur findings suggest that multiparous women, regardless of maternal age, and primiparous women aged ≤ 29 years are associated with a high probability of successful vaginal twin delivery.

Indexed as

Delivery, ObstetricPregnancy, TwinAdultFemaleHumansMaternal AgeParityPregnancyRetrospective StudiesCesarean sectionMode of deliveryPredictive factorsTrial of laborTwin pregnancyVaginal delivery

Identifiers

PMID41361411
PMCPMC12797642

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.