Evidence map›Paper›PMID 41361268›Full record

ArticleBMC public health2025

The individual and joint effects of long-term exposure to temperature and relative humidity on blood pressure: a prospective cohort study in China.

Guanhao He, Zhongguo Huang, Yan Shi, Zishan Huang, Di Wang, Mengen Guo, Yanfei Guo, Jiahong Xu, JianXiong Hu, Xiaomei Dong and 5 more

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The Japanese Society of Hypertension Practical Consensus Guidelines for Seasonal Blood Pressure Management.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  2. [Environmental relative humidity, frailty, and risk of incident stroke among middle-aged and older adults in China: A prospective cohort study].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Guanhao He *Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, No.601 West, Huangpu Road, Tianhe District, Guangzhou, 510632, China.
Zhongguo Huang *Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, No.601 West, Huangpu Road, Tianhe District, Guangzhou, 510632, China.
Yan Shi *Shanghai Municipal Centre for Disease Control and Prevention, Shanghai, 200336, China.
Zishan HuangDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, No.601 West, Huangpu Road, Tianhe District, Guangzhou, 510632, China.
Di WangDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, No.601 West, Huangpu Road, Tianhe District, Guangzhou, 510632, China.
Mengen GuoDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, No.601 West, Huangpu Road, Tianhe District, Guangzhou, 510632, China.
Yanfei GuoShanghai Municipal Centre for Disease Control and Prevention, Shanghai, 200336, China.
Jiahong XuDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, No.601 West, Huangpu Road, Tianhe District, Guangzhou, 510632, China.
JianXiong HuDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, No.601 West, Huangpu Road, Tianhe District, Guangzhou, 510632, China.
Xiaomei DongDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, No.601 West, Huangpu Road, Tianhe District, Guangzhou, 510632, China.
Jianpeng XiaoGuangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, 511430, China.
Ziqiang LinDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, No.601 West, Huangpu Road, Tianhe District, Guangzhou, 510632, China.
Tao LiuDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, No.601 West, Huangpu Road, Tianhe District, Guangzhou, 510632, China.
Fan WuShanghai Medical College, Fudan University, 130 Dong-An Road, Xuhui District, Shanghai, 200032, China. wufan@shmu.edu.cn.
Wenjun MaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, No.601 West, Huangpu Road, Tianhe District, Guangzhou, 510632, China. mawj@gdiph.org.cn.

Funding

Medical and Young Elite Scientists Sponsorship Program by CAST 2022QNRC001National Key Research and Development Program of China 2023YFC3605000National Natural Science Foundation of China 42075173National Natural Science Foundation of China 42505175
6 · The paper itself

Abstract

backgroundThe opportunity of long-term exposure to non-optimal temperature and relative humidity (RH) may increase which might contribute to elevations in blood pressure (BP). This study aimed to examine the joint effect of long-term exposure to temperature and RH on BP which help better adaption to climate change.

methodsData were collected from 9272 participants in global AGEing and adult health cohort study across eight provinces in China from 2007 to 2019. Annual meteorological data were treated as indicators which derived from European Centre for Medium-Range Weather Forecasts atmospheric reanalysis (ERA5). Generalized linear mixed models (GLMM) and quantile-based g-computation models were employed to estimate the individual and joint associations between long-term exposure to temperature and RH with BP.

resultsIn joint effect analysis, we found a U-shaped pattern. The minimum blood pressure percentile (MBPP) for both systolic blood pressure (SBP) and diastolic blood pressure (DBP) was observed at a temperature of approximately 15.4 °C and RH of 72.8%. Compared to MBPP, exposure to 4.6 °C and 57.9% was associated with increases of 12.05mmHg (95%CI:11.63-12.42mmHg) and 6.67mmHg (95%CI:6.43-6.88mmHg) in SBP and DBP, respectively. Exposure to 22.5 °C and 79.2% was associated with increases of 11.75mmHg (95%CI:10.32-13.08mmHg) and 6.47mmHg (95%CI:5.65-7.25mmHg) in of SBP and DBP, respectively. People < 60 years old, female and hypertensive patients not taking antihypertensive medication were more susceptible to mixture exposure to low temperature and low RH. Additionally, the effect of dry-cold event on BP was higher than that of wet-cold, wet-hot, and dry-hot events.

conclusionThe associations between long-term co-exposure to temperature and RH and BP exhibited a U-shaped curve. Individuals under 60 years old, females, and hypertensive patients not taking antihypertensive medication were more susceptible to dry-cold events.

Indexed as

Blood PressureEnvironmental ExposureHumidityTemperatureAdultAgedChinaFemaleHumansHypertensionMaleMiddle AgedProspective StudiesAmbient temperatureBlood pressureJoint effectsLong-term exposureRelative humidity

Identifiers

PMID41361268
PMCPMC12683869

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.