ArticleMagnetic resonance in medicine2026
Repeatability of Rapid Human Cardiac Phosphorus MRSI (
Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
purposePCr/ATP ratio is determined at 7 T typically using Fourier-transform based magnetic resonance spectroscopic imaging sequences (FT-MRSI). These sequences require acquisition times longer than desirable for inclusion in cardiac clinical trials. Concentric ring trajectory (CRT-MRSI) has been described as an accelerated alternative k-space sampling method. In this work we aim to establish the inter- and intra-session repeatability of three different CRT protocols and compare their voxel-based PCr/ATP ratios to compartment-based PCr/ATP values extracted with spectroscopy using a linear algebraic model (SLAM) method.
methodsSeven healthy volunteers were scanned twice on two different days. Each time a 6.5-min 3D FT-MRSI acquisition with 10 × 10 × 10 resolution was followed by a 2.5-min CRT-MRSI with matched resolution, a 1.5-min CRT-MRSI with matched resolution, and a 6.9-min CRT-MRSI with 12 × 12 × 12 resolution. Spectra from a mid-septal voxel and the cardiac compartment were fitted with the OXSA toolbox. PCr/ATP ratio was quantified for inter- and intra-session repeatability analysis.
resultsPaired repeated measurements were not significantly different within subjects. Good inter- and intra-session agreement was observed between FT-MRSI and each CRT-MRSI protocol. CRT-MRSI protocols all had larger coefficients of repeatability (CoR) than FT-MRSI. CRT-SLAM-based PCr/ATP values had lower CoR than voxel-based data except for 2.5-min CRT-SLAM, and high-resolution CRT-SLAM had lower inter-session CoR compared to FT-MRSI (1.42 vs. 2.21).
conclusionWe established the repeatability of CRT-MRSI-based PCr/ATP values and showed higher SNR and lower CoR for CRT-SLAM. Our findings allow shorter
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.