ArticleNPP - digital psychiatry and neuroscience2025
Multimodal objective assessment of impulsivity in healthy and mood disorder participants.
Article in NPP - digital psychiatry and neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Transdiagnostic neuromodulation of impulsivity: current status and future trajectories.Translational psychiatry · 2025Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Impulsivity represents an individual's tendency to act on urges without sufficient forethought. Heightened impulsivity is a hallmark of many mental health disorders. Objective impulsivity assessments could improve risk evaluation, diagnosis, and behavioral outcome monitoring in impulsivity-related health disorders. Towards objective impulsivity assessment, in this work, we identify impulsivity correlates in objective measurements, investigate their complementarity, and contrast impulsivity mechanisms across health conditions. We analyzed behavioral tests, heart rate variability (HRV), and fMRI-based brain connectivity in 227 healthy participants and 34 participants with mood disorders. Impulsivity dimensions had complementary correlates in objective measurements, with fMRI providing the strongest correlates. Multimodal assessment provided high r-squared (adjusted) values in modeling impulsivity of the mood disorder participants (e.g., r-squared of 0.73, p < 0.001 for attentional impulsivity) but low r-squared for healthy participants (the best r-squared being 0.17, p < 0.001 for sensation seeking impulsivity). The differing association between impulsivity dimensions across the two populations likely indicates a health condition-specific impulsivity mechanism across populations. The complementary nature of objective impulsivity correlates across populations demonstrates the distributed signature of multidimensional impulsivity, likely capturing the complexity of behavioral modeling.
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Registered trials
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