Evidence map›Paper›PMID 41360987›Full record

ReviewNature reviews. Cancer2026

N

Hanzhi Luo, Michael G Kharas, Samie R Jaffrey

Abstract readReview
In one paragraph

Review in Nature reviews. Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Targeting MYC-Driven Cancers: From Oncogenic Addiction to Therapeutic Vulnerability.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Emerging roles of mJournal of assisted reproduction and genetics · 2026
    Review
  7. Article
  8. Review
  9. Article
  10. Targeting mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  11. Article
  12. Elevated mBMC cancer · 2026
    Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hanzhi LuoMolecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Hanzhi.luo@fccc.edu.ORCID http://orcid.org/0000-0002-4906-967X
Michael G KharasMolecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. kharasm@mskcc.org.ORCID http://orcid.org/0000-0002-1165-6991
Samie R JaffreyDepartment of Pharmacology, Weill Cornell Medicine, New York, NY, USA. srj2003@med.cornell.edu.ORCID http://orcid.org/0000-0003-3615-6958

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Center for Multi-Scale Analysis of the Human EpitranscriptomeRM1HG011563 · NHGRI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SAMIE R JAFFREY, Kathryn D Meyer · 2021 to 2026
$22.2M
New mechanisms and technologies for understanding post-transcriptional gene regulation in neuronsR35NS111631 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI SAMIE R JAFFREY · 2019 to 2026
$8.6M
Mechanisms of epitranscriptomic regulation in cancerR01CA186702 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SAMIE R JAFFREY, Michael Kharas · 2014 to 2026
$8.0M
Uncovering the role for MSI2 network in hematopoietic stem cellsR01DK101989 · NIDDK · SLOAN-KETTERING INST CAN RESEARCH · PI Michael Kharas, Vijay Ganesh Sankaran · 2014 to 2026
$6.2M
Characterizing the MSI2 network in leukemiaR01CA193842 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI KHARAS, MICHAEL · 2015 to 2025
$4.1M
Identification of therapeutic targets for leukemia stem cells in AML-iPSC modelsR01CA225231 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KHARAS, MICHAEL, PAPAPETROU, EIRINI · 2018 to 2022
$3.2M
Interrogation of the oxidative-stress-induced leukemia program in vivo usingmetabolic imagingR01CA283578 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Kayvan R Keshari, Michael Kharas · 2023 to 2026
$3.0M
Molecular and genetic analysis of novel Slicer-dependent miRNA pathways in bloodR01HL135564 · NHLBI · SLOAN-KETTERING INST CAN RESEARCH · PI KHARAS, MICHAEL, LAI, ERIC C · 2017 to 2020
$2.9M
Understanding resistance mechanisms to protein arginine methyltransransferase Inhibitors in LymphomaR01CA274249 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Michael Kharas · 2023 to 2026
$2.8M
Defining the molecular basis controlling hematopoietic stem cell symmetric and asymmetric divisionsR00DK128602 · NIDDK · RESEARCH INST OF FOX CHASE CAN CTR · PI Hanzhi Luo · 2024 to 2026
$747k
Defining the molecular basis controlling hematopoietic stem cell symmetric and asymmetric divisions -supplementK99DK128602 · NIDDK · SLOAN-KETTERING INST CAN RESEARCH · PI LUO, HANZHI · 2021 to 2023
$235k
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA186702NCI NIH HHS R01 CA193842NCI NIH HHS R01 CA225231NCI NIH HHS R01 CA274249NCI NIH HHS R01 CA283578NHGRI NIH HHS RM1 HG011563NHLBI NIH HHS R01 HL135564NIDDK NIH HHS K99 DK128602NIDDK NIH HHS R00 DK128602NIDDK NIH HHS R01 DK101989NINDS NIH HHS R35 NS111631
6 · The paper itself

Abstract

N

Indexed as

AdenosineNeoplasmsAnimalsGene Expression Regulation, NeoplasticHumansMethyltransferasesRNA, MessengerRNA Processing, Post-TranscriptionalTumor MicroenvironmentAdenosineMethyltransferasesMETTL3 protein, humanN-methyladenosineRNA, Messenger

Identifiers

PMID41360987
PMCPMC13142248

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.