Evidence map›Paper›PMID 41360809›Full record

ReviewNPJ vaccines2025

Establishing long-lasting vaccine immunity: insights from mRNA and adjuvanted protein platforms.

Andrea-Clemencia Pineda-Peña, Kohei Hasegawa, Vincent Pavot, Catherine Berry, Behazine Combadière, Guadalupe Cortes-Garcia, Adrian B McDermott, Saranya Sridhar

Abstract readReview
In one paragraph

Review in NPJ vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andrea-Clemencia Pineda-Peña *Sanofi Vaccines R&D, Marcy-l'Étoile, Auvergne-Rhône-Alpes, France.
Kohei Hasegawa *Sanofi Vaccines R&D, Waltham, MA, USA. Kohei.Hasegawa@sanofi.com.
Vincent PavotSanofi Vaccines R&D, Marcy-l'Étoile, Auvergne-Rhône-Alpes, France.
Catherine BerrySanofi Vaccines R&D, Marcy-l'Étoile, Auvergne-Rhône-Alpes, France.
Behazine CombadièreSanofi Vaccines R&D, Marcy-l'Étoile, Auvergne-Rhône-Alpes, France.
Guadalupe Cortes-GarciaSanofi Vaccines R&D, Waltham, MA, USA.
Adrian B McDermottSanofi Vaccines R&D, Marcy-l'Étoile, Auvergne-Rhône-Alpes, France.
Saranya SridharSanofi Vaccines R&D, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Durable vaccine-induced immunity is the basis of long-term protection against infection and disease. This review covers three topics. First, we describe the immunological foundations of durable response and its determinants (e.g., vaccine design, host, and pathogen factors). Second, we summarize the current evidence regarding the durable immune responses conferred by mRNA- and adjuvanted protein-based vaccine platforms. Lastly, we discuss the challenges in developing durable mRNA vaccines and outline future considerations.

Identifiers

PMID41360809
PMCPMC12717083

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.