Evidence map›Paper›PMID 41360459›Full record

ArticleBMJ open2025

What is the postoperative prognosis of proximal humeral fractures in China? Protocol for a multicentre prospective cohort study (CAST).

Qiuke Wang, Yijie Chai, Haoning He, Zeming Zhan, Rongguang Ao, Langqing Zeng, Qiang Chen, Yanjie Liu, Ming Zhang, Yuanyang Gu and 3 more

Abstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Qiuke WangDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated toShanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0001-6439-6380
Yijie ChaiDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated toShanghai Jiao Tong University School of Medicine, Shanghai, China.
Haoning HeDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated toShanghai Jiao Tong University School of Medicine, Shanghai, China.
Zeming ZhanDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated toShanghai Jiao Tong University School of Medicine, Shanghai, China.
Rongguang AoDepartment of Orthopaedics, Shanghai Seventh People's Hospital, Shanghai, China.
Langqing ZengDepartment of Orthopaedics, Zhuhai City People's Hospital, The Affiliated Hospital of Beijing Institute of Technology, Zhuhai Clinical Medical College of Jinan University, Zhuhai, Guangdong, China.
Qiang ChenDepartment of Orthopaedics, Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Yanjie LiuDepartment of Orthopaedics, First People's Hospital of Foshan, Foshan, Guangdong, China.
Ming ZhangDepartment of Orthopaedics, Wuhan Fourth Hospital, Wuhan, Hubei, China.
Yuanyang GuDepartment of Orthopaedics, Yancheng Third People's Hospital, Yancheng, Jiangsu, China.
Longfei XiaoDepartment of Orthopaedics, Sheyang County People's Hospital, Yancheng, Jiangsu, China.
Longxiang ShenDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated toShanghai Jiao Tong University School of Medicine, Shanghai, China.
Yunfeng ChenDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated toShanghai Jiao Tong University School of Medicine, Shanghai, China drchenyunfeng@sina.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionProximal humeral fractures are increasingly common, particularly among older people, whereas the prognosis of surgical treatments for these fractures remains substantially uncertain. In China, where the ageing population is rapidly growing, high-quality prospective data on surgical outcomes, complications and cost-effectiveness are lacking. To address this gap, we propose to initiate a prospective, multicentre cohort study on surgical treatment for proximal humeral fractures in China-Cohort of Acute Shoulder Trauma (CAST) study. METHODS AND ANALYSIS: The CAST is a multicentre, prospective cohort study enrolling patients with acute proximal humeral fractures undergoing surgical treatments at eight hospitals in China between May 2024 and December 2029. Patients can receive any of the surgical treatment methods which include percutaneous Kirschner wire fixation, external fixation, open reduction and internal fixation using locking plates or intramedullary nails, suture anchors and shoulder arthroplasty. We will collect patient-reported outcome measures (Quick Disabilities of the Arm, Shoulder and Hand), Constant-Murley, American Shoulder and Elbow Surgeons, EuroQol 5-Dimension and Visual Analogue Scale), physical examination results, imaging assessments (based on X-rays, ultrasound, CT and MRI scans), laboratory tests (including inflammatory cytokines) and data on medical costs. We will follow patients at 1 day, and at 1 month, 3 months, 6 months, 12 months and 24 months postoperatively. The planned sample size is 1500 patients. ETHICS AND DISSEMINATION: The study protocol has been approved by the Ethics Committee of Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University (Approval No. 2024-ky-104(K)). Written informed consent will be obtained from all participants. Findings from the CAST study will be disseminated through peer-reviewed journals and academic conferences. STUDY REGISTRATION NUMBER: ChiCTR2500109651.

Indexed as

Fracture FixationShoulder FracturesChinaFracture Fixation, InternalHumansMulticenter Studies as TopicPatient Reported Outcome MeasuresPostoperative ComplicationsPrognosisProspective StudiesFractures, BoneORTHOPAEDIC & TRAUMA SURGERYShoulder

Identifiers

PMID41360459
PMCPMC12684081

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.