ArticleArquivos de neuro-psiquiatria2025
Electrophysiological and biochemical evaluations of neuropathy risk in oral levodopa versus levodopa/carbidopa intestinal gel treatment.
Article in Arquivos de neuro-psiquiatria, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Letter on: "Electrophysiological and Biochemical Evaluations of Neuropathy Risk in Oral Levodopa versus Levodopa/Carbidopa Intestinal Gel Treatment".Arquivos de neuro-psiquiatria · 2026Article
- Reply to the Letter on: "Electrophysiological and Biochemical Evaluations of Neuropathy Risk in Oral Levodopa versus Levodopa/Carbidopa Intestinal Gel Treatment".Arquivos de neuro-psiquiatria · 2026Article
- Comment on "Electrophysiological and Biochemical Evaluations of Neuropathy Risk in Oral Levodopa versus Levodopa/Carbidopa Intestinal Gel Treatment".Arquivos de neuro-psiquiatria · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The association between levodopa treatment and neuropathy in Parkinson's disease (PD) remains controversial, particularly when comparing the oral and intestinal administration routes.To compare the electrophysiological and biochemical changes in patients receiving oral levodopa or levodopa/carbidopa intestinal gel (LCIG) and to determine their association with neuropathy development.The current prospective cross-sectional study included 32 PD patients (18 oral and 14 LCIG). Demographic features, disease duration, Hoehn and Yahr (H&Y) stage, Unified Parkinson's Disease Rating Scale (UPDRS) scores, biochemical parameters (vitamin B12, folate, homocysteine), and electrophysiological values were recorded. Nerve conduction studies (NCSs) of the median, ulnar, peroneal, tibial, and sural nerves were performed unilaterally, using reference values from our neurophysiology laboratory.The LCIG group presented significantly higher doses of levodopa (
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