Trial reportAnesthesia progress2025
Comparing Etizolam and Music Distraction on Inferior Alveolar Nerve Block Success in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial.
Trial report in Anesthesia progress, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Anxious patients report more pain during endodontic therapy. This clinical trial aimed to assess the effect of etizolam vs music distraction on inferior alveolar nerve block (IANB) success in patients with high dental anxiety and symptomatic irreversible pulpitis in a mandibular molar. Methods: A total of 110 patients participated in this randomized clinical trial. Preoperative anxiety was assessed using the Modified Corah Dental Anxiety Scale (MDAS). Patients were randomly allocated to a placebo, etizolam, or music distraction (MD) group. Patients in the placebo and etizolam groups consumed either a placebo or etizolam (0.5 mg), respectively, 1 hour before local anesthesia delivery. Patients in the MD group listened to their self-selected music via headphones throughout the visit. All patients received a standard IANB with 2% lidocaine with 1:200,000 epinephrine. Intraoperative pain levels were assessed using the Heft Parker visual analogue scale (HP-VAS). No or mild pain (0-54 mm on HP-VAS) was counted as success, whereas moderate to severe pain (55-170 mm) during endodontic procedure was considered as IANB failure. Results: χ2 test revealed that patients in the MD group exhibited significantly higher local anesthetic success compared to the other 2 groups (P < .01). No significant difference was found in IANB success between the placebo and etizolam groups. Conclusion: IANB success was significantly higher in patients who listened to music during endodontic therapy than in patients who received etizolam or placebo.
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