Evidence map›Paper›PMID 41359960›Full record

ArticleOrganic letters2026

Photoredox/Nickel Dual-Catalyzed Asymmetric C-Alkylation of Nitroalkanes with α-Bromoketones.

Sina Rezazadeh, Raphael S Kim, Donald A Watson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Organic letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sina RezazadehDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.ORCID 0000-0002-7090-7519
Raphael S KimDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.
Donald A WatsonDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.ORCID 0000-0003-4864-297X

Funding

This renovation project will create over 1455 sq. ft. of state- of-the-art reseaP20GM104316 · NIGMS · UNIVERSITY OF DELAWARE · PI SCHMITZ, KARL ROBERT · 2014 to 2024
$26.8M
Pilot Research Subproject ProgramP30GM110758 · NIGMS · UNIVERSITY OF DELAWARE · PI PATEL, SANDEEP · 2014 to 2018
$5.8M
Cross Couplings of Amine and Alcohol Derivatives to Give Enantioenriched ProductsR01GM111820 · NIGMS · UNIVERSITY OF DELAWARE · PI WATSON, MARY P · 2014 to 2018
$1.6M
Transition Metal Catalyzed Methods for Preparing Nitroalkanes and Alkyl AminesR01GM102358 · NIGMS · UNIVERSITY OF DELAWARE · PI WATSON, DONALD ALLEN · 2014 to 2018
$1.6M
Novel Reactions of Electrophilic Nitrogen for Preparing Bioactive MoleculesR01GM145617 · NIGMS · UNIVERSITY OF DELAWARE · PI WATSON, DONALD ALLEN · 2022 to 2025
$1.4M
Q-Exactive Orbitrap LC-MC/MS SystemS10OD016267 · OD · UNIVERSITY OF DELAWARE · PI JOHNSTON, MURRAY V · 2013 to 2013
$573k
High Performance Digital NMR SpectrometerS10RR026962 · NCRR · UNIVERSITY OF DELAWARE · PI FOX, JOSEPH M · 2010 to 2010
$500k
NCRR NIH HHS S10 RR026962NIGMS NIH HHS P20 GM104316NIGMS NIH HHS P30 GM110758NIGMS NIH HHS R01 GM102358NIGMS NIH HHS R01 GM111820NIGMS NIH HHS R01 GM145617NIH HHS S10 OD016267
6 · The paper itself

Abstract

A stereoselective method for alkylating nitroalkanes with α-bromoketones using nickel/photoredox dual catalysis is described. The mild and functional-group-tolerant conditions allow the formation of complex and highly enantioenriched β-nitroketone products that hold promising utility as precursors for the formation of biologically relevant compounds.

Indexed as

AlkanesHydrocarbons, BrominatedKetonesNickelNitro CompoundsAlkylationCatalysisMolecular StructureOxidation-ReductionPhotochemical ProcessesStereoisomerismAlkanesHydrocarbons, BrominatedKetonesNickelNitro Compounds

Identifiers

PMID41359960
PMCPMC12814514

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.