Evidence map›Paper›PMID 41359866›Full record

Trial reportJournal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]2026

Evaluating the Efficiency and Tooth Sensitivity of a Novel Whitening Strip: A Randomized, Double-Blind Controlled Trial.

Rui-Xin Chen, Yu-Jie Lan, Li Guo, Xin-Yi Zhang, De-Qin Yang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.], 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rui-Xin ChenNorthern Department of Endodontics, Stomatological Hospital of Chongqing Medical University, Chongqing, China.
Yu-Jie LanNorthern Department of Endodontics, Stomatological Hospital of Chongqing Medical University, Chongqing, China.
Li GuoNorthern Department of Endodontics, Stomatological Hospital of Chongqing Medical University, Chongqing, China.
Xin-Yi ZhangNorthern Department of Endodontics, Stomatological Hospital of Chongqing Medical University, Chongqing, China.
De-Qin YangNorthern Department of Endodontics, Stomatological Hospital of Chongqing Medical University, Chongqing, China.ORCID https://orcid.org/0009-0003-1401-7276

Funding

Chongqing Medical UniversityNational Natural Science Foundation of China PT30960419
6 · The paper itself

Abstract

objectiveThis randomized controlled clinical trial was to evaluate the tooth whitening efficacy and tooth sensitivity of a novel whitening strips with 3% hydrogen peroxide and 1.5% potassium nitrate. MATERIALS AND

methodsNinety six participants were randomly assigned into two groups: an experimental group using LESENING Whitening Strips with 3% hydrogen peroxide and 1.5% potassium nitrate (n = 41), and the control group using Crest 3D Whitestrips only with 3% hydrogen peroxide (n = 41). Participants attached whitening strips to the teeth' buccal surface for 30 min once daily at home for 28 days continuously. Tooth sensitivity was evaluated using the Schiff score. Tooth color and color change were assessed using a spectrophotometer (CIELAB coordinates L*, a*, b*, ΔE*

resultsIn color differences (ΔE*

conclusionLESENING whitening strips with 3% hydrogen peroxide and 1.5% potassium nitrate were esthetically effective. Moreover, the LESENING group showed lower tooth sensitivity change than the Crest group. CLINICAL RELEVANCE: The use of LESENING whitening strips with 3% hydrogen peroxide and 1.5% potassium nitrate for at-home dental whitening could reduce the risk of dentin hypersensitivity without compromising whitening efficacy.

trial registrationISRCTN registry number: ISRCTN30027746.

Indexed as

Dentin SensitivityTooth BleachingTooth Bleaching AgentsAdultColorDouble-Blind MethodFemaleHumansHydrogen PeroxideMaleNitratesPotassium CompoundsSpectrophotometryTooth DiscolorationCrest whitestripsHydrogen PeroxideNitratesPotassium Compoundspotassium nitrateTooth Bleaching Agentsdentin desensitizing agentsestheticshydrogen peroxidetooth sensitivitytooth whitening

Identifiers

PMID41359866
PMCPMC13471807

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.