Evidence map›Paper›PMID 41359852›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

PFAS-contaminated drinking water harms infants.

Robert Baluja, Bo Guo, Wesley Howden, Ashley Langer, Derek Lemoine

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. How to destroy "forever chemicals" for good.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. PFAS-contaminated drinking water harms infants.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Robert BalujaCornerstone Research, Los Angeles, CA 90013.
Bo GuoDepartment of Hydrology and Atmospheric Sciences, University of Arizona, Tucson, AZ 85719.
Wesley HowdenPrivate address, New Orleans, LA, 70117.ORCID 0000-0003-2117-1872
Ashley LangerDepartment of Economics, University of Arizona, Tucson, AZ 85721.
Derek LemoineDepartment of Economics, University of Arizona, Tucson, AZ 85721.ORCID 0000-0002-1298-9472

Funding

National Science Foundation (NSF) SES-2149335
6 · The paper itself

Abstract

There is evidence of widespread human exposure to per- and polyfluoroalkyl substances (PFAS) but limited evidence of the human health impacts of this exposure. Using data on New Hampshire births from 2010-2019, we show that mothers receiving water that had flowed beneath a PFAS-contaminated site, as opposed to comparable mothers receiving water that had flowed toward a PFAS-contaminated site, had 191% [95% CI: 83-298%] higher first-year infant mortality (611 [268-955] additional first-year deaths per 100k births); 168% [42-294%] more births before 28 wk of gestational age (466 [116-817] additional such births per 100k births); and 180% [57-302%] more births with weight below 1,000 g (607 [192-1022] additional such births per 100k births). Extrapolating to the contiguous U.S., PFAS contamination imposes annual social costs of approximately $8 billion. These health costs are substantially larger than current outside estimates of the cost of removing PFAS from the public water supply.

Indexed as

Drinking WaterFluorocarbonsMaternal ExposureWater Pollutants, ChemicalAdultEnvironmental ExposureFemaleHumansInfantInfant MortalityInfant, NewbornMaleNew HampshirePregnancyDrinking WaterFluorocarbonsWater Pollutants, Chemicalbirthweightinfant mortalityPFASreproductive healthwater pollution

Identifiers

PMID41359852
PMCPMC12718334

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.