Evidence map›Paper›PMID 41359406›Full record

ArticleJournal of medicinal chemistry2025

Evaluation of Bifunctional, PSMA-Targeted Triazamacrocycle-Picolinates Compatible with the

Owen M Glaser, Hannah Goerlach, Megan V Salek, Eduardo Aluicio-Sarduy, Mallory J Gork, Dariusz Śmiłowicz, Edith Amason, Jason C Mixdorf, Todd E Barnhart, Jonathan W Engle and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Single Molecule EuJournal of the American Chemical Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Owen M GlaserDepartment of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53705, United States.
Hannah GoerlachDepartment of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53705, United States.
Megan V SalekDepartment of Medical Physics, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, Wisconsin 53705, United States.
Eduardo Aluicio-SarduyDepartment of Medical Physics, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, Wisconsin 53705, United States.
Mallory J GorkDepartment of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53705, United States.
Dariusz ŚmiłowiczDepartment of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53705, United States.
Edith AmasonDepartment of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53705, United States.
Jason C MixdorfDepartment of Medical Physics, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, Wisconsin 53705, United States.
Todd E BarnhartDepartment of Medical Physics, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, Wisconsin 53705, United States.
Jonathan W EngleDepartment of Medical Physics, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, Wisconsin 53705, United States.ORCID 0000-0002-3399-7228
Eszter BorosDepartment of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53705, United States.ORCID 0000-0002-4186-6586

Funding

Harnessing the Radiochelation Chemistry of Theranostic, Rare Earth IsotopesR01EB032349 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI Eszter Boros · 2022 to 2026
$1.9M
NIBIB NIH HHS R01 EB032349
6 · The paper itself

Abstract

The development of matched diagnostic and therapeutic radiopharmaceuticals─theranostic pairs─has emerged as a promising strategy to advance personalized nuclear medicine. However, many current systems rely on chemically distinct elements such as the

Indexed as

Antigens, SurfaceGlutamate Carboxypeptidase IIPicolinic AcidsRadioisotopesRadiopharmaceuticalsAnimalsChelating AgentsFluorine RadioisotopesHumansLutetiumMiceTissue DistributionAntigens, SurfaceChelating AgentsFluorine RadioisotopesFOLH1 protein, humanGlutamate Carboxypeptidase IILutetiumLutetium-177Picolinic AcidsRadioisotopesRadiopharmaceuticals

Identifiers

PMID41359406
PMCPMC12751015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.