Evidence map›Paper›PMID 41359271›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2025

Sex-related presentation, outcome, and treatment in CICU: the SPOTlight STUDY.

Alessia d'Aiello, Mattia Brecciaroli, Simone Filomia, Daniela Pedicino, Marco Giuseppe Del Buono, Gianluigi Saponara, Rocco Antonio Montone, Gaetano Pinnacchio, Lorenzo Genuardi, Laura Antenucci and 5 more

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Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Alessia d'AielloDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy.
Mattia BrecciaroliDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy.
Simone FilomiaDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy.
Daniela PedicinoDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy.
Marco Giuseppe Del BuonoDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy.
Gianluigi SaponaraDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy.
Rocco Antonio MontoneDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy.
Gaetano PinnacchioDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy.
Lorenzo GenuardiDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy.
Laura AntenucciFondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Jacopo LenkowiczFondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Giovanna LiuzzoDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy.
Carlo TraniDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy.
Francesco BurzottaDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy.
Tommaso SannaDepartment of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy. Tommaso.sanna@policlinicogemelli.it.ORCID http://orcid.org/0000-0002-5760-6885

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

key pointsWHAT IS ALREADY KNOWN: • Sex-related differences in cardiovascular disease presentation, management, and outcomes have been increasingly recognized in recent years. • Women with acute cardiovascular conditions often receive less aggressive diagnostic and therapeutic interventions compared to men, particularly in the setting of acute coronary syndromes. WHAT THIS STUDY ADDS: • This study provides a comprehensive evaluation of sex-related differences in a contemporary cohort of patients admitted to the Cardiac Intensive Care Unit (CICU), highlighting distinct admission patterns and management disparities. • Women with cardiovascular disease tend to be older at presentation, exhibit different risk factor profiles, and show distinct clinical manifestations compared to men. • It identifies higher mortality rates for women with STEMI and pulmonary embolism, emphasizing the need for improved recognition and tailored management of sex-specific differences in acute cardiovascular care.

Indexed as

Cardiac Intensive Care Unit (CICU)Cardiogenic shockGender-specific health strategiesSex differences

Identifiers

PMID41359271

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.