ArticleLangenbeck's archives of surgery2025
Outcomes of pancreatoduodenectomy in underlying liver cirrhosis: a single institution experience and literature review.
Article in Langenbeck's archives of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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9 authors.
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Abstract
introductionPancreatoduodenectomy (PD) is a complex procedure associated with up to 20-30% morbidity and 1-2% mortality. In the present study, we aimed to evaluate the outcomes of PD in patients with cirrhotic liver and assessed predictors of perioperative morbidity and mortality. MATERIALS AND
methodsThis is a retrospective study from a prospectively maintained database. Amongst the patients who underwent PD between January 2013 till June 2024, only patients who had underlying cirrhotic liver were included in the study.
resultsA total of 24 patients were included. On binary logistic regression history of pancreatitis in the preoperative period (OD-25.8), stent block (OD-64.9), cholangitis (OD-273), and preoperative platelets less than 1.37(OD-40), preoperative INR more than 1.31(OD-40) and platelets count on POD1 less than 1.23 lakhs (OD-40) were associated with mortality.
conclusionPatients with clinically significant portal hypertension with thrombocytopenia and a deranged coagulation profile are associated with a high risk of mortality.
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