Evidence map›Paper›PMID 41359167›Full record

ReviewCellular and molecular life sciences : CMLS2025

Stress-Induced calcium mishandling in cardiac (Patho)physiology.

Dan J Bare, Xun Ai

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dan J BareDepartment of Physiology and Cell Biology, College of Medicine, Wexner Medical Center, The Ohio State University, 333 W. 10th Avenue, Columbus, 43210, OH, USA.
Xun AiDepartment of Physiology and Cell Biology, College of Medicine, Wexner Medical Center, The Ohio State University, 333 W. 10th Avenue, Columbus, 43210, OH, USA. ai.87@osu.edu.ORCID http://orcid.org/0000-0002-7677-2643

Funding

Heart-platelet crosstalk: JNK, AF, and thrombogenesisR01HL146744 · NHLBI · RUSH UNIVERSITY MEDICAL CENTER · PI Xun Ai, Yuchi Han · 2019 to 2026
$3.2M
Atrial and blood JNK in Postoperative AFR01HL168728 · NHLBI · OHIO STATE UNIVERSITY · PI Xun Ai · 2023 to 2026
$2.7M
The KChIP2-JNK2 axis as a therapeutic target for sudden cardiac deathR01HL174911 · NHLBI · OHIO STATE UNIVERSITY · PI Xun Ai, Isabelle Deschenes · 2024 to 2026
$2.3M
The JNK2-NLRP3 nexus in atrial fibrillation and its anti-AF therapeutic potentialsR01AA031056 · NIAAA · OHIO STATE UNIVERSITY · PI Xun Ai · 2024 to 2026
$1.8M
Mechanistic characterization of JNK2α variants in alcohol-caused heart failureR01AA031805 · NIAAA · OHIO STATE UNIVERSITY · PI Xun Ai · 2025 to 2026
$1.2M
NHLBI NIH HHS R01 HL146744NHLBI NIH HHS R01HL146744NHLBI NIH HHS R01 HL168728NHLBI NIH HHS R01HL168728NHLBI NIH HHS R01 HL174911NIAAA NIH HHS AA031805NIAAA NIH HHS R01 AA031056NIAAA NIH HHS R01AA031056NIAAA NIH HHS R01 AA031805
6 · The paper itself

Abstract

Calcium (Ca

Indexed as

CalciumCalcium SignalingHeartMyocardiumMyocytes, CardiacStress, PhysiologicalAnimalsHeart DiseasesHumansCalciumCalcium homeostasisCardiac dysfunctionIon channelsIschemia-ReperfusionMyocardial infarctionSarcoplasmic reticulum

Identifiers

PMID41359167
PMCPMC12686274

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.