Evidence map›Paper›PMID 41358753›Full record

ArticleJournal of clinical microbiology2026

Blood culture utilization and impact of stewardship practices during a national blood culture bottle shortage at a cancer center.

Rosemary C She, Jeffrey M Bender, Vinod Pullarkat, Sanjeet S Dadwal

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rosemary C SheDepartment of Pathology, City of Hope Comprehensive Cancer Center, Duarte, California, USA.ORCID 0000-0002-8773-1687
Jeffrey M BenderDepartment of Pediatrics, City of Hope Comprehensive Cancer Center, Duarte, California, USA.
Vinod PullarkatDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope Comprehensive Cancer Center, Duarte, California, USA.
Sanjeet S DadwalDepartment of Medicine, City of Hope Comprehensive Cancer Center, Duarte, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Formulating safe and effective diagnostic stewardship guidance for blood cultures in immunocompromised patients is challenging due to limited data and high risk of infectious complications. A 2024 global shortage in blood culture bottles (BD Diagnostics) necessitated the implementation of blood culture stewardship, including at our tertiary care cancer center. This was a retrospective pre-post intervention study of the effects of diagnostic stewardship at a stand-alone cancer center during a 5-month period of the 2024 blood culture bottle shortage compared to the same 5-month unaffected period in 2023. Interventions included discontinuation of an ordering set for persistent fever, modification of an ordering set for new fever to recommend two sets of blood cultures for initial workup, and issuing revised blood culture ordering guidance to providers, phlebotomists, and nurses with repeated educational efforts. Stewardship interventions led to decreased blood culture utilization by 36.3% (from 14,021 to 8,932), while the number of patients tested remained similar. Greatest reductions in utilization occurred in inpatient encounters and with follow-up blood cultures. There was a trend toward increasing blood culture positivity following intervention, excluding potential contaminants (7.1% vs 7.6%,

Indexed as

Antimicrobial StewardshipBlood CultureAgedCancer Care FacilitiesFemaleHumansMaleMiddle AgedNeoplasmsRetrospective Studiesdiagnostic stewardshipmortalitypersistent feversepsistest utilizationtransplant

Identifiers

PMID41358753
PMCPMC12802142

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.