Evidence map›Paper›PMID 41358738›Full record

ArticleBlood advances2026

Impact of Perforin 1 A91V germ line background in patients with aggressive B-NHL treated with R-CHOP.

Onur Cetin, Igor Kos, Evi Regitz, Moritz Bewarder, Torben M Rixecker, Eugen Tausch, Eva C Schwarz, Johanna Jansky, Vadim Lesan, Claudia Schormann and 21 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Onur CetinJosé Carreras Center for Immuno- and Gene Therapy and Department of Internal Medicine I, Saarland University Medical School, Homburg, Germany.ORCID 0009-0007-3441-7743
Igor KosJosé Carreras Center for Immuno- and Gene Therapy and Department of Internal Medicine I, Saarland University Medical School, Homburg, Germany.
Evi RegitzJosé Carreras Center for Immuno- and Gene Therapy and Department of Internal Medicine I, Saarland University Medical School, Homburg, Germany.
Moritz BewarderJosé Carreras Center for Immuno- and Gene Therapy and Department of Internal Medicine I, Saarland University Medical School, Homburg, Germany.
Torben M RixeckerDepartment of Internal Medicine V, Saarland University Medical School, Homburg, Germany.ORCID 0000-0003-1417-7571
Eugen TauschSektion CLL, Klinik für Innere Medizin III, Universitätsklinikum Ulm, Ulm, Germany.
Eva C SchwarzBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, Germany.ORCID 0000-0002-6503-4864
Johanna JanskyBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, Germany.ORCID 0000-0002-7076-1265
Vadim LesanJosé Carreras Center for Immuno- and Gene Therapy and Department of Internal Medicine I, Saarland University Medical School, Homburg, Germany.
Claudia SchormannJosé Carreras Center for Immuno- and Gene Therapy and Department of Internal Medicine I, Saarland University Medical School, Homburg, Germany.
Frank NeumannJosé Carreras Center for Immuno- and Gene Therapy and Department of Internal Medicine I, Saarland University Medical School, Homburg, Germany.
Markus LoefflerInstitute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.
Michael HallekDepartment I of Internal Medicine and German CLL Study Group, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.ORCID 0000-0002-7425-4455
Kirsten FischerDepartment I of Internal Medicine and German CLL Study Group, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Sylvia ZöphelBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, Germany.ORCID 0000-0001-7601-8889
Annette M StaigerDepartment of Clinical Pathology, Robert Bosch Hospital, Stuttgart, Germany.ORCID 0000-0002-5896-3200
German OttDepartment of Clinical Pathology, Robert Bosch Hospital, Stuttgart, Germany.
Konstantinos ChristofyllakisJosé Carreras Center for Immuno- and Gene Therapy and Department of Internal Medicine I, Saarland University Medical School, Homburg, Germany.
Joerg T BittenbringJosé Carreras Center for Immuno- and Gene Therapy and Department of Internal Medicine I, Saarland University Medical School, Homburg, Germany.
Viola PoeschelJosé Carreras Center for Immuno- and Gene Therapy and Department of Internal Medicine I, Saarland University Medical School, Homburg, Germany.
Dominic Kaddu-MulindwaJosé Carreras Center for Immuno- and Gene Therapy and Department of Internal Medicine I, Saarland University Medical School, Homburg, Germany.
Philipp B StaberJosé Carreras Center for Immuno- and Gene Therapy and Department of Internal Medicine I, Saarland University Medical School, Homburg, Germany.ORCID 0000-0001-6729-7708
Rudy LigtvoetDepartment I of Internal Medicine and German CLL Study Group, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.ORCID 0000-0001-6546-0911
Sandra RobrechtDepartment I of Internal Medicine and German CLL Study Group, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.ORCID 0000-0001-8848-6655
Marita ZiepertInstitute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.
Norbert SchmitzDepartment of Hematology, Oncology, and Pneumology, University Hospital Muenster, Münster, Germany.
Markus HothBiophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, Germany.
Christoph KesselTranslational Inflammation Research, Department Pediatric Rheumatology and Immunology, University Hospital Muenster, Muenster, Germany.
Stephan StilgenbauerSektion CLL, Klinik für Innere Medizin III, Universitätsklinikum Ulm, Ulm, Germany.
Bettina AltmannInstitute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.
Lorenz ThurnerJosé Carreras Center for Immuno- and Gene Therapy and Department of Internal Medicine I, Saarland University Medical School, Homburg, Germany.ORCID 0000-0002-8167-2989

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41358738
PMCPMC12915228

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.