Evidence map›Paper›PMID 41358731›Full record

ArticleApplied and environmental microbiology2026

Discovery of MBL-AB01: a novel antibacterial xanthone antibiotic with high activity against methicillin-resistant

Kristin Fløgstad Degnes, Anna Nordborg, Giang-Son Nguyen, Guro Kruge Nærdal, Tonje Marita Bjerkan Heggeset, Peter Molesworth, Sigrid Hakvåg, Randi Aune, Vu To Nakstad, Johan Evenäs and 5 more

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kristin Fløgstad DegnesSINTEF Industry, Biotechnology and Nanomedicine, Trondheim, Norway.ORCID 0000-0003-1538-840X
Anna NordborgSINTEF Industry, Biotechnology and Nanomedicine, Trondheim, Norway.ORCID 0000-0001-5507-0012
Giang-Son NguyenSINTEF Industry, Biotechnology and Nanomedicine, Trondheim, Norway.ORCID 0000-0001-5730-3326
Guro Kruge NærdalSINTEF Industry, Biotechnology and Nanomedicine, Trondheim, Norway.ORCID 0009-0000-4938-8577
Tonje Marita Bjerkan HeggesetSINTEF Industry, Biotechnology and Nanomedicine, Trondheim, Norway.ORCID 0000-0002-1221-8598
Peter MolesworthSINTEF Industry, Biotechnology and Nanomedicine, Trondheim, Norway.ORCID 0000-0002-7483-0109
Sigrid HakvågDepartment of Biotechnology and Food Science, NTNU Norwegian University of Science and Technology, Trondheim, Norway.ORCID 0000-0003-3287-2412
Randi AuneSINTEF Industry, Biotechnology and Nanomedicine, Trondheim, Norway.
Vu To NakstadSINTEF Industry, Biotechnology and Nanomedicine, Trondheim, Norway.ORCID 0000-0003-3157-2346
Johan EvenäsRG Discovery AB, Lund, Sweden.ORCID 0009-0003-6491-9083
Klara JonassonRG Discovery AB, Lund, Sweden.ORCID 0009-0006-9262-8031
Trond Erling EllingsenSINTEF Industry, Biotechnology and Nanomedicine, Trondheim, Norway.
Alexander WentzelSINTEF Industry, Biotechnology and Nanomedicine, Trondheim, Norway.ORCID 0000-0002-9420-1959
Geir Klinkenberg *SINTEF Industry, Biotechnology and Nanomedicine, Trondheim, Norway.ORCID 0000-0002-5165-1722
Håvard Sletta *SINTEF Industry, Biotechnology and Nanomedicine, Trondheim, Norway.ORCID 0000-0002-5635-5674

Funding

HORIZON EUROPE European Innovation Council 101046941MarBiLeads/Norges Forskningsråd 208482/O10Norges Forskningsråd 157319Norges Forskningsråd 248885/O70
6 · The paper itself

Abstract

A novel compound denoted MBL-AB01 was isolated from a marine

Indexed as

ActinobacteriaAnti-Bacterial AgentsMethicillin-Resistant Staphylococcus aureusXanthonesMicrobial Sensitivity TestsMultigene FamilyAnti-Bacterial AgentsXanthonesbioreactorbiosynthetic gene clusterdrug discoveryminimum inhibitory concentrationMRSAStaphylococcus aureusxanthones

Identifiers

PMID41358731
PMCPMC12838262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.