Evidence map›Paper›PMID 41358671›Full record

ArticleGut microbes2025

Infection with gut parasites correlates with gut microbiome diversity across human populations in Africa.

Mirabeau M Ngwese, Bayode R Adegbite, Jeannot F Zinsou, J Liam Fitzstevens, Victor T Schmidt, Paul Alvyn N Moure, Moustapha N Maloum, Alexander V Tyakht, Kelsey E Huus, Nicholas D Youngblut and 3 more

Abstract read
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mirabeau M NgweseDepartment of Microbiome Science, Max Planck Institute for Biology, Tübingen, Germany.ORCID 0000-0001-7354-7128
Bayode R AdegbiteCentre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné, Gabon.ORCID 0000-0003-4208-6212
Jeannot F ZinsouCentre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné, Gabon.ORCID 0000-0003-4719-8299
J Liam FitzstevensDepartment of Microbiome Science, Max Planck Institute for Biology, Tübingen, Germany.ORCID 0000-0002-0102-7243
Victor T SchmidtDepartment of Microbiome Science, Max Planck Institute for Biology, Tübingen, Germany.ORCID 0000-0002-2110-2538
Paul Alvyn N MoureCentre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné, Gabon.ORCID 0000-0002-9703-4893
Moustapha N MaloumCentre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné, Gabon.ORCID 0000-0001-8213-8465
Alexander V TyakhtDepartment of Microbiome Science, Max Planck Institute for Biology, Tübingen, Germany.ORCID 0000-0002-7358-2537
Kelsey E HuusDepartment of Microbiome Science, Max Planck Institute for Biology, Tübingen, Germany.ORCID 0000-0002-7580-1924
Nicholas D YoungblutDepartment of Microbiome Science, Max Planck Institute for Biology, Tübingen, Germany.ORCID 0000-0002-7424-5276
Peter G KremsnerCentre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné, Gabon.ORCID 0000-0002-3926-4113
Ayola A AdegnikaCentre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné, Gabon.ORCID 0000-0003-3197-5946
Ruth E LeyDepartment of Microbiome Science, Max Planck Institute for Biology, Tübingen, Germany.ORCID 0000-0002-9087-1672

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Soil-transmitted helminths (STH) are common in (sub)tropical regions and primarily affect impoverished populations. These parasites reside in the gut, where they interact with both the microbiota and host immunity. Clinical STH detection is laborious and often not performed within the context of gut microbiome studies. Here, we present a proof-of-concept study assessing whether fecal metagenome data could be used to assess STH infection, and to relate STH infection to microbiome features. We leveraged 310 gut metagenomes obtained from mother-child pairs in two different locations in Gabon: one rural and one semi-urban, and assessed the presence of four STH species (

Indexed as

Gastrointestinal MicrobiomeHelminthiasisHelminthsAnimalsAscaris lumbricoidesBacteriaBiodiversityChildChild, PreschoolFecesFemaleGabonHumansMaleMetagenomeMetagenomicsalpha diversitybeta diversitygut microbiomehost-microbiome interactionsmicrobiome-parasite associationsqPCRsequencingSoil-transmitted helminths

Identifiers

PMID41358671
PMCPMC12688249

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.