Evidence map›Paper›PMID 41358503›Full record

ArticleNeurorehabilitation and neural repair2025

Cognitive Impairments Impact Functional Mobility in Stroke Survivors.

Anjali Tiwari, Stefan Delmas, Sharon N Poisson, Brian Kaiser, Manfred Diehl, Neha Lodha

Abstract read
In one paragraph

Article in Neurorehabilitation and neural repair, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anjali TiwariDepartment of Health and Exercise Science, Colorado State University, Fort Collins, Colorado, USA.ORCID 0009-0009-1468-3504
Stefan DelmasDepartment of Health and Exercise Science, Colorado State University, Fort Collins, Colorado, USA.
Sharon N PoissonDepartment of Neurology, School of Medicine, University of Colorado, Aurora, Colorado, USA.
Brian KaiserDepartment of Neurology, School of Medicine, University of Colorado, Aurora, Colorado, USA.
Manfred DiehlDepartment of Human Development and Family Studies, Colorado State University, Fort Collins, Colorado, USA.
Neha LodhaDepartment of Health and Exercise Science, Colorado State University, Fort Collins, Colorado, USA.

Funding

Investigating cognitive-motor variability to predict driving performance in stroke survivors with MCIK01AG070327 · NIA · COLORADO STATE UNIVERSITY · PI LODHA, NEHA · 2021 to 2025
$705k
NIA NIH HHS K01 AG070327
6 · The paper itself

Abstract

BackgroundFunctional mobility is essential for maintaining independence and relies on both motor and cognitive processes. Although the impact of motor impairments on functional mobility in stroke survivors has been extensively studied, the influence of post-stroke cognitive impairments has been largely overlooked. The aim of the current study is 2-fold. First, to determine the impact of post-stroke cognitive impairments on functional mobility across a broad spectrum of tasks. Second, to determine if cognitive impairment has a differential impact on various forms of mobility.MethodForty individuals with stroke (20 cognitively normal and 20 cognitively impaired) and 30 healthy older adults participated in the study. Participants performed cognitive, motor, and mobility assessments. Cognitive tests included global and domain-specific assessments on an extensive neuropsychological battery. Motor tests included the Modified Rankin Scale and strength assessments. Functional mobility included the assessment of balance, overground walking, and driving in a simulator.ResultsFindings indicated that stroke survivors with cognitive impairment demonstrated significant deteriorations in functional mobility across multiple domains, compared to both cognitively normal stroke survivors and healthy older adults. Cognitive impairment significantly interferes with functional mobility, with driving showing greatest deterioration compared to balance and walking performance. Notably, this impact is independent of the level of disability and motor strength.ConclusionCognitive impairments in stroke survivors are associated with significant mobility disturbances, with the most pronounced deficits in driving performance. This study highlights the importance of including and prioritizing cognitive evaluation and intervention for enhancing functional mobility and independence in stroke survivors.

Indexed as

Cognitive DysfunctionStrokeAgedAged, 80 and overAutomobile DrivingFemaleHumansMaleMiddle AgedNeuropsychological TestsPostural BalanceSurvivorsbalancecognitive functiondrivingwalking

Identifiers

PMID41358503
PMCPMC12686676

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.