Evidence map›Paper›PMID 41358246›Full record

ReviewFrontiers in public health2025

Nicotine pouches and youth: emerging patterns and potential cardiovascular risks.

Shaun Abid, Abhinav Aggarwal, Freddy Duarte, Samdish Sethi, Sumedh Iyengar, Stuart Zarich

Abstract readReview
In one paragraph

Review in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shaun AbidDepartment of Internal Medicine, Yale New Haven Health, Bridgeport Hospital, Bridgeport, CT, United States.
Abhinav AggarwalDepartment of Cardiology, Yale New Haven Health, Bridgeport Hospital, Bridgeport, CT, United States.
Freddy DuarteDepartment of Cardiology, Houston Methodist Hospital, Houston, TX, United States.
Samdish SethiDepartment of Cardiology, Yale New Haven Health, Bridgeport Hospital, Bridgeport, CT, United States.
Sumedh IyengarDepartment of Internal Medicine, Yale New Haven Health, Bridgeport Hospital, Bridgeport, CT, United States.
Stuart ZarichDepartment of Cardiology, Yale New Haven Health, Bridgeport Hospital, Bridgeport, CT, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid rise in nicotine pouch use among teens and young adults signals a shift in nicotine consumption with significant public health implications. Marketed as discreet and "tobacco free," these products are often perceived as safer alternatives to smoking, yet their cardiovascular risks remain largely unexamined. Emerging concerns center on the high nicotine content, efficient bloodstream delivery, and growing rates of dual or poly-use with other nicotine products. Adolescents, in particular, face heightened vulnerability due to ongoing physiological development and increased addiction susceptibility. This review explores the potential cardiovascular consequences of nicotine pouch use in youth, emphasizing the urgency of evidence-based research to inform clinical guidance, regulatory action, and prevention strategies.

Indexed as

Cardiovascular DiseasesHeart Disease Risk FactorsNicotineAdolescentHumansYoung AdultNicotineadolescentscardiovascular risknicotine addictionnicotine pouchestobacco harm reductionyoung adults

Identifiers

PMID41358246
PMCPMC12675456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.