ArticleFrontiers in public health2025
Impact of sense of coherence and social support on disease activity in Crohn's disease: a network analysis.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Sense of coherence (SOC) and social support are key factors in managing chronic diseases, but their specific impact on disease activity in Crohn's disease (CD) remains unclear. Network analysis provides a novel approach to understanding the complex relationships among psychological and clinical variables. Objective: This study aimed to use network analysis to explore the relationship between SOC and social support and disease activity in CD patients across different body weight categories, considering that body weight influences disease prognosis, nutritional status, and treatment needs. Methods: A cross-sectional study was conducted among 276 hospitalized CD patients from a tertiary hospital in Zhejiang. Participants were categorized as underweight, normal weight, or overweight based on BMI. SOC (SOC-13), social support (MSPSS), and disease activity (simplified CDAI) were assessed using validated tools. Disease activity was measured using a simplified Crohn's Disease Activity Index (CDAI), which is an abbreviated version of the full CDAI with a reduced number of items (5 instead of 8). Partial correlation networks were constructed for each BMI group using graphical LASSO and visualized via the Fruchterman-Reingold algorithm. Centrality and bridge expected influence were calculated to identify key variables, and Network Comparison Tests were conducted across BMI groups. Results: Comprehensibility and family support emerged as central nodes in normal and overweight groups, while manageability was central in underweight patients. Bridge analyses indicated that manageability and family support linked SOC, social support, and disease activity. No significant structural differences were found among BMI groups ( Conclusion: Manageability and family support were identified as central and bridging factors in CD patients, regardless of BMI. Targeted interventions to strengthen these factors may enhance disease management and patient outcomes. However, given the exploratory nature of the results, which is needed to confirm these findings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.