Photolysis of ortho-Nitrobenzyl Esters: Kinetics and Substituent Effects.

Anthony L Fink, Alexander G Groß, Florian Puch, Robert Geitner

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In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anthony L FinkGroup of Physical Chemistry/Catalysis, Department of Natural Sciences and Mathematics, Technische Universität Ilmenau, Weimarer Str. 32, 98693 Ilmenau, Germany.

Alexander G GroßGroup of Physical Chemistry/Catalysis, Department of Natural Sciences and Mathematics, Technische Universität Ilmenau, Weimarer Str. 32, 98693 Ilmenau, Germany.ORCID https://orcid.org/0000-0002-3996-5446

Florian PuchPlastics Technology Group, Department of Mechanical Engineering, Thuringian Center of Innovation in Mobility, Technische Universität Ilmenau, Gustav-Kirchhoff Str. 5, 98693 Ilmenau, Germany.ORCID https://orcid.org/0000-0002-7668-2138

Robert GeitnerGroup of Physical Chemistry/Catalysis, Department of Natural Sciences and Mathematics, Technische Universität Ilmenau, Weimarer Str. 32, 98693 Ilmenau, Germany.ORCID https://orcid.org/0000-0001-5419-4451

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ortho-Nitrobenzyl (oNB) esters are widely employed as photolabile protecting groups and linkers in diverse applications ranging from materials science to chemical biology. While their photochemical decomposition mechanism has been well studied, a comprehensive understanding of the structure-property relationships governing their photolysis kinetics remains lacking. In this study, the synthesis and kinetic analysis of 11 novel oNB esters with varying ester and aromatic substituents are reported. Using time-resolved NMR spectroscopy, we determined first-order rate constants for the photochemical cleavage of each compound under UV irradiation. A clear correlation between the reaction rate and the acidity (p

Identifiers

PMID41358119

DOI10.1021/acsomega.5c08422

PMCPMC12676297

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.