ArticleClinical interventions in aging2025
Association Between Nephrolithiasis and the Prevalence of Sarcopenia in Chinese Older Adults: A Cross-Sectional Study Using Propensity Score Matching.
Article in Clinical interventions in aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Sarcopenia is an age-related condition characterized by loss of muscle mass and function. Nephrolithiasis represents a prevalent urological disorder that imposes a substantial burden on healthcare resources. However, the association between sarcopenia and nephrolithiasis remains poorly characterized. Methods: A total of 2586 older adults were included in this cross-sectional study. We used the univariate and multivariate logistic regression models to assess the relationship between nephrolithiasis and sarcopenia. Additionally, stratified analyses and propensity score matching (PSM) were performed to account for potential confounding factors. Results: The prevalence of sarcopenia in the present study was 7.2%. In Model 4, which integrated for all relevant covariates, nephrolithiasis was associated with approximately a 190% increased prevalence of sarcopenia compared to non-nephrolithiasis patients (OR: 2.912, 95% CI: 1.708-4.968, Conclusion: Our findings demonstrate that nephrolithiasis is positively related to the potential risk of sarcopenia in Chinese older adults. This finding indicates that nephrolithiasis may contribute to sarcopenia development, thereby emphasizing that prevention and intervention strategies for sarcopenia should account for the adverse effects of nephrolithiasis.
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