Characteristics of Extremely Preterm Infants Undergoing Procedural Closure of Patent Ductus Arteriosus: A Retrospective Cohort Study.

N Jayakumar, G Uthayakumaran, S M Boyd, J Mervis, R Halliday, A Webb, H Popat

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Article in International journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

N JayakumarGrace Centre for Newborn Intensive Care, The Children's Hospital at Westmead, Westmead, Australia.ORCID https://orcid.org/0000-0003-1008-3439

G UthayakumaranGrace Centre for Newborn Intensive Care, The Children's Hospital at Westmead, Westmead, Australia.ORCID https://orcid.org/0000-0002-5947-1208

S M BoydGrace Centre for Newborn Intensive Care, The Children's Hospital at Westmead, Westmead, Australia.ORCID https://orcid.org/0000-0001-7766-1817

J MervisGrace Centre for Newborn Intensive Care, The Children's Hospital at Westmead, Westmead, Australia.ORCID https://orcid.org/0000-0003-0571-9383

R HallidayGrace Centre for Newborn Intensive Care, The Children's Hospital at Westmead, Westmead, Australia.ORCID https://orcid.org/0009-0003-1316-6165

A WebbThe University of Sydney, Sydney, Australia.ORCID https://orcid.org/0000-0001-8435-4436

H PopatGrace Centre for Newborn Intensive Care, The Children's Hospital at Westmead, Westmead, Australia.ORCID https://orcid.org/0000-0002-6991-9686

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patent ductus arteriosus (PDA) is the most common cardiac lesion in preterm newborns. When medical management of a hemodynamically significant PDA is unsuccessful or contraindicated, infants are referred for either transcatheter device closure (TCDC) or surgical ligation. Our objective was to describe the characteristics and outcomes of these infants. Methods: A retrospective cohort study of infants ≤ 30 weeks' gestation undergoing either TCDC or surgical ligation for PDA from January 2009 to April 2023 was undertaken, in a surgical neonatal intensive care unit. Baseline demographics, echocardiographic data, procedural complications, and neonatal outcomes were obtained. Results: A total of 136 infants were included. At the time of referral for PDA closure, infants were 5-145 days old, with a corrected gestational age of 24-50 weeks and PDA diameter of 1.5-4.1 mm. TCDC of PDA was performed in 15 neonates compared with 121 neonates who underwent surgical ligation. Procedural complications and important neonatal outcomes were similar for both groups. While the number of infants undergoing TCDC is increasing, there is a decreasing trend in the total number of surgical PDA closures. Conclusions: This study demonstrates that there is variability in the preclosure demographics and echocardiography characteristics of infants ≤ 30 weeks' gestation referred for procedural PDA closure.

Indexed as

infantsneonatespatent ductus arteriosuspretermsurgical ligationtranscatheter device closure

Identifiers

PMID41357829

DOI10.1155/ijpe/5558870

PMCPMC12680452

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.