Evidence map›Paper›PMID 41357820›Full record

ArticleFrontiers in sports and active living2025

The effect of doping, anti-doping measures, and sociological factors on the annual distribution of all-time top performances in short, middle, and long-distance running.

Dora Dragcevic, Jelena Jaksic, Lukas Libric, Ozana Jaksic, Delfa Radic-Kristo, Vlatka Pandzic, Ozren Jaksic

Abstract read
In one paragraph

Article in Frontiers in sports and active living, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Dora DragcevicDepartment of Hematology, University Hospital Merkur, Zagreb, Croatia.
Jelena JaksicSchool of Medicine, University of Zagreb, Zagreb, Croatia.
Lukas LibricSchool of Medicine, University of Zagreb, Zagreb, Croatia.
Ozana JaksicSchool of Medicine, University of Zagreb, Zagreb, Croatia.
Delfa Radic-KristoDepartment of Hematology, University Hospital Merkur, Zagreb, Croatia.
Vlatka PandzicSchool of Medicine, University of Zagreb, Zagreb, Croatia.
Ozren JaksicSchool of Medicine, University of Zagreb, Zagreb, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scientific advancements, doping, anti-doping strategies, and sociological factors all influence athletic performance. This retrospective study aimed to analyze how different variables affect the annual distribution of all-time top performances from 1968-2023 in men's and women's running disciplines with different physiological demands (100 m-anaerobic, 5,000 m-aerobic, 800 m-mixed aerobic-anaerobic). A public database, https://www.alltime-athletics.com, with results linked to doping already excluded, was used. The annual distribution of top performances was modeled using negative binomial distribution to assess the influence of continuous and categorical variables, including doping availability (e.g., tetrahydrogestrinone, erythropoietin), anti-doping measures (e.g., Athlete Biological Passport modules, out-of-competition testing), and sociological factors (e.g., Olympic years). Steroid doping related variables showed significant effects on the annual distribution of top performances across almost all tested men's and women's disciplines, with a significant negative influence of testosterone limitations in women's 800 m, as well as a negative influence of the steroid module of the Athlete Biological Passport in women's 100 m and men's 800 m and 5,000 m disciplines. Blood doping related variables, including the positive influence of erythropoietin availability and the negative influence of the hematological module of the Athlete Biological Passport, demonstrated significant effects on performance in both 800 m disciplines. Olympic years emerged as a positive factor in the majority of tested disciplines, while the COVID-19 pandemic showed no significant influence. Despite strict anti-doping measures, our findings reveal a complex interaction of doping practices, regulatory frameworks, and social factors that continue to influence trends in elite athletic performance.

Indexed as

androgen anabolic steroidsAthlete Biological Passportblood dopingerythropoietinrunningtestosteronetetrahydrogestrinonetop performance

Identifiers

PMID41357820
PMCPMC12678324

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.