Evidence map›Paper›PMID 41357786›Full record

ArticleJournal of arrhythmia2025

Safety and Clinical Outcomes of Transvenous Lead Extraction for Cardiac Device Infections in the Very Elderly.

Khalid Sawalha, John P Marenco, Laurence M Epstein, Shayal Pundlik, Kyle Gobeil, Marshal Fox, Fadi Chalhoub

Abstract read
In one paragraph

Article in Journal of arrhythmia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Khalid SawalhaDepartment of Cardiology UMass Chan Medical School-Baystate Springfield Massachusetts USA.ORCID https://orcid.org/0000-0002-2643-0434
John P MarencoDepartment of Cardiology UMass Chan Medical School-Baystate Springfield Massachusetts USA.
Laurence M EpsteinDepartment of Cardiology, Zucker School of Medicine at Hofstra/Northwell North Shore University Hospital Manhasset New York USA.
Shayal PundlikDepartment of Cardiology UMass Chan Medical School-Baystate Springfield Massachusetts USA.
Kyle GobeilDepartment of Cardiology UMass Chan Medical School-Baystate Springfield Massachusetts USA.
Marshal FoxDepartment of Cardiology UMass Chan Medical School-Baystate Springfield Massachusetts USA.
Fadi ChalhoubDepartment of Cardiology UMass Chan Medical School-Baystate Springfield Massachusetts USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The increasing use of cardiac implantable electronic devices (CIEDs) has led to a rise in transvenous lead extractions (TLE), particularly for device-related infections. The elderly represent a growing subgroup undergoing TLE, but data on their outcomes are limited. Objectives: To evaluate the safety and in-hospital outcomes of TLE in patients aged ≥ 80 years with device-related infections. Methods: We analyzed the National Inpatient Sample (NIS) from 2016 to 2020 to identify hospitalizations involving TLE for device-related infections. Patients were stratified by age: < 80 years and ≥ 80 years. The primary outcome was in-hospital mortality. Secondary outcomes included major procedural complications and length of stay. Multivariate logistic regression identified independent predictors of in-hospital mortality and complications. Results: Among 30 670 patients who underwent TLE, 6530 (21.3%) were aged ≥ 80 years. In-hospital mortality did not differ significantly between groups (4.0% vs. 4.6%, Conclusion: Elderly patients undergoing TLE for infections had similar in-hospital mortality and complication rates compared to younger patients. Age alone should not preclude TLE. However, increased risks of stroke and bleeding warrant targeted perioperative assessment. Further studies are needed to assess long-term outcomes in this population.

Indexed as

device infectionelderlytransvenous lead extraction

Identifiers

PMID41357786
PMCPMC12681079

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