Evidence map›Paper›PMID 41357765›Full record

ArticleRadiology advances2025

Detection and severity stratification of chronic liver disease using magnetic resonance intravoxel incoherent motion and elastography.

Damiano Catucci, Sandro Urs von Daeniken, Verena Carola Obmann, Annalisa Berzigotti, Lukas Ebner, Johannes Thomas Heverhagen, Andreas Christe, Peter Vermathen, Adrian Thomas Huber

Abstract read
In one paragraph

Article in Radiology advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Damiano CatucciDepartment of Diagnostic, Interventional and Pediatric Radiology, Inselspital, University Hospital Bern, Bern, 3010, Switzerland.ORCID https://orcid.org/0000-0001-6053-3181
Sandro Urs von DaenikenDepartment of Diagnostic, Interventional and Pediatric Radiology, Inselspital, University Hospital Bern, Bern, 3010, Switzerland.
Verena Carola ObmannDepartment of Diagnostic, Interventional and Pediatric Radiology, Inselspital, University Hospital Bern, Bern, 3010, Switzerland.
Annalisa BerzigottiDivision of Hepatology, Department of Visceral Surgery and Medicine, Inselspital, University Hospital Bern, Bern, 3010, Switzerland.
Lukas EbnerDepartment of Diagnostic, Interventional and Pediatric Radiology, Inselspital, University Hospital Bern, Bern, 3010, Switzerland.ORCID https://orcid.org/0000-0001-5117-6047
Johannes Thomas HeverhagenDepartment of Diagnostic, Interventional and Pediatric Radiology, Inselspital, University Hospital Bern, Bern, 3010, Switzerland.
Andreas ChristeDepartment of Diagnostic, Interventional and Pediatric Radiology, Inselspital, University Hospital Bern, Bern, 3010, Switzerland.ORCID https://orcid.org/0000-0002-2355-2591
Peter VermathenMagnetic Resonance Methodology Group, Institute of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital Bern, Bern, 3010, Switzerland.ORCID https://orcid.org/0000-0001-8649-1098
Adrian Thomas HuberDepartment of Diagnostic, Interventional and Pediatric Radiology, Inselspital, University Hospital Bern, Bern, 3010, Switzerland.ORCID https://orcid.org/0000-0001-6146-8238

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: With chronic liver disease (CLD) rising globally, noninvasive methods are needed to stratify early, intermediate, and advanced CLD with and without clinically significant portal hypertension (CSPH). Purpose: To analyze the combined diagnostic value of intravoxel incoherent motion (IVIM) and liver stiffness (LS) from magnetic resonance elastography (MRE) for CLD stage discrimination vs secondary single-parameter analyses. Materials and methods: This retrospective cross-sectional study included 185 patients who underwent 3T liver MRI, including MRE and IVIM, between March 2016 and November 2023. Patients with CLD were grouped based on their liver fibrosis degree into early CLD (F0-F1; Results: In total, 185 patients (median age: 55 years, interquartile range 25%-75%: 45-63 years; 94 men) were evaluated. All parameters differed significantly between all groups ( Conclusion: IVIM and MRE are useful for characterizing CLD and CSPH. Combining D from IVIM with LS from MRE improves diagnostic accuracy compared to MRE alone.

Indexed as

chronic liver diseasecirrhosisdiffusiondiffusion-weighted imagingfibrosisintravoxel incoherent motion imagingmagnetic resonance elastographyMRIperfusionportal hypertension

Identifiers

PMID41357765
PMCPMC12677949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.