ArticleWorld journal of gastrointestinal surgery2025
Clinical utility of a novel concentrated enteral formula in patients undergoing colorectal cancer surgery: A randomized controlled trial.
Article in World journal of gastrointestinal surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundCompared to standard hospital meals, nutritional intervention using recovery K5 (RK5), a concentrated liquid diet, offers a comprehensive immunonutritional profile, suggesting its potential effectiveness in preventing surgical site infections (SSIs) after gastrointestinal surgery.
aimTo investigate the usefulness of RK5 in patients undergoing elective colorectal cancer surgery, focusing on postoperative infections and nutritional status.
methodsThis single-center, open-label, randomized, parallel-group comparative trial was conducted at Department of Gastrointestinal Surgery, Nippon Medical School Hospital, between February 2023 and August 2024. Forty patients with colorectal cancer were randomly assigned in a 1:1 ratio to either the nutritional intervention or the control group. The intervention group received 800 kcal/day of RK5 administered orally instead of breakfast and dinner (400 kcal per serving) 2 days prior to surgery, whereas the control group received only standard meals. Postoperative infection, nutritional status, and bowel habits were assessed.
resultsNo cases of remote infection were observed. SSIs occurred in one of the 17 patients (5.9%) in the intervention group and six of the 18 patients (33.3%) in the control group, with an odds ratio of 0.125 (95% confidence interval: 0.013-1.181,
conclusionSupplemental nutrition using RK5 may help prevent SSIs in patients undergoing elective colorectal cancer surgery and should be considered as a potential option for perioperative nutritional management.
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