ArticleWorld journal of gastrointestinal surgery2025
Clinicopathological features of patients undergoing surgery for pancreatic cancer with very early postoperative recurrence.
Article in World journal of gastrointestinal surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Very early recurrence in pancreatic cancer: Redefining prognostic markers and surveillance strategies.World journal of gastrointestinal surgery · 2026Article
- Very early recurrence after pancreatic cancer resection: Unmasking the "biological R2" enigma and rethinking prognostic paradigms.World journal of gastrointestinal surgery · 2025Article
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Authors and funding
8 authors.
Funding
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Abstract
backgroundPancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy, with approximately 50% of patients experiencing recurrence within 1-year post-surgery. Very early recurrence (VER), defined as recurrence within 12 weeks, is an emerging concept.
aimTo investigate clinicopathological characteristics and predictive factors for VER in patients with PDAC.
methodsA retrospective cohort study was conducted on 553 patients who underwent pancreatic surgery for PDAC at a single high-volume center between February 2019 and December 2024. Patients with VER (group 1,
resultsGroup 1 patients were younger (65 ± 16.85 years
conclusionPoorly differentiated tumors are a key predictor of VER, linked to higher mortality. Machine learning enhances predictive accuracy, and molecular studies are needed to elucidate VER mechanisms. Tailored surveillance and multi-institutional validation are recommended.
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