Evidence map›Paper›PMID 41357516›Full record

ReviewFrontiers in medicine2025

Research progress on hyperbaric oxygen therapy for refractory peptic ulcer disease.

Ze-Ming Chen, Wei-Feng Li, Xi-Qiu Yu, Xiao Tang, Qin-Hua Yang, Xiao-Lan Wei

Abstract readReview
In one paragraph

Review in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ze-Ming Chen *Department of Gastroenterology, Shenzhen Luohu People's Hospital, Shenzhen, Guangdong, China.
Wei-Feng Li *Department of Gastroenterology, Shenzhen Luohu People's Hospital, Shenzhen, Guangdong, China.
Xi-Qiu YuDepartment of Gastroenterology, Shenzhen Luohu People's Hospital, Shenzhen, Guangdong, China.
Xiao TangDepartment of Gastroenterology, Shenzhen Luohu People's Hospital, Shenzhen, Guangdong, China.
Qin-Hua YangDepartment of Gastroenterology, Shenzhen Luohu People's Hospital, Shenzhen, Guangdong, China.
Xiao-Lan WeiDepartment of Gastroenterology, Shenzhen Luohu People's Hospital, Shenzhen, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Refractory peptic ulcer disease (RPUD) refers to gastric and duodenal ulcers that remain unhealed after 8-12 weeks drug treatment or are associated with complications despite drug treatment. Peptic ulcer disease is non-responsive to many treatments, has high recurrence rates, and often results in long-term pain, thus posing a persistent clinical challenge. Although the application of proton pump inhibitors has improved the healing rate and prognosis of patients with RPUD, drug efficacy is often limited by the emergence of drug resistant

Indexed as

Helicobacter pylorihyperbaric oxygen therapy (HBOT)mechanismrefractory peptic ulcer disease (RPUD)review

Identifiers

PMID41357516
PMCPMC12678276

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.