Evidence map›Paper›PMID 41357493›Full record

ArticleFrontiers in medicine2025

Comparative efficacy and safety of dexmedetomidine and midazolam for conscious sedation in blind nasotracheal intubation: a randomized controlled trial.

Zhengyu Li, Man Wang, Jing Zhang, Hongjin Wu, Xue Zhang, Hong Luo, Heng Yang

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhengyu Li *Department of Anesthesiology, The Third Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Man Wang *Department of Anesthesiology, The Third Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Jing Zhang *Department of Anesthesiology, The Third Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Hongjin Wu *Department of Anesthesiology, The Third Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Xue Zhang *Department of Anesthesiology, The Third Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Hong LuoDepartment of Anesthesiology, The Third Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Heng YangDepartment of Anesthesiology, The Third Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the safety and efficacy of dexmedetomidine amnestic analgesia slow induction for blind nasotracheal intubation (BNTI) in oral and maxillofacial surgery. Methods: Sixty patients undergoing oral and maxillofacial surgery were randomly divided into the dexmedetomidine (DEX) group (1.0 μg/kg, 15 min of infusion + pethidine 1.0 mg/kg) and the midazolam (MID) group (0.02 mg/kg + pethidine 1.0 mg/kg). The intubation time was recorded, and heart rate (HR), mean arterial pressure (MAP), bispectral index (BIS) and pulse oximeter oxygen saturation (SpO Results: Compared with the MID group, the intubation time in the DEX group was shorter and the P Conclusion: Dexmedetomidine used for blind nasotracheal intubation for oral and maxillofacial surgery can provide comprehensive anesthesia effects, significantly reduce the stress response of tracheal intubation and the dosage of intraoperative opioids, while maintaining good hemodynamic stability.

Indexed as

airway managementblind nasotracheal intubationconscious sedationdexmedetomidinemidazolamsedative comparison

Identifiers

PMID41357493
PMCPMC12678327

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.