Evidence map›Paper›PMID 41357410›Full record

ReviewWorld journal of transplantation2025

Beyond futility: The history and potential of liver transplantation in cholangiocarcinoma.

Lynn Affarah, Sreelakshmi Kotha, Philip Berry

Abstract readReview
In one paragraph

Review in World journal of transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lynn AffarahDepartment of Hepatology, Guy's and St Thomas' Hospital, London SE1 7JD, United Kingdom.
Sreelakshmi KothaDepartment of Hepatology, Guy's and St Thomas' Hospital, London SE1 7JD, United Kingdom. sreelakshmi.kotha@gstt.nhs.uk.
Philip BerryDepartment of Hepatology, Guy's and St Thomas' Hospital, London SE1 7JD, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cholangiocarcinoma (CCA) is a rare type of cancer which arises from the bile duct epithelium and carries a poor prognosis. One of the main risk factors in the Western world is primary sclerosing cholangitis. Surgical resection has traditionally been the only curative treatment but can only be offered to patients with early disease, excluding those with locally advanced disease. Despite initial poor outcomes, liver transplantation (LT) has evolved as a viable treatment for a select group of patients with CCAs that are deemed unresectable. This review aims to explore the evolution of the role of LT in patients with CCA.

Indexed as

CholangiocarcinomaExtrahepatic cholangiocarcinomaIntrahepatic cholangiocarcinomaLiver transplantationPrimary sclerosing cholangitis

Identifiers

PMID41357410
PMCPMC12679222

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.