ArticleWorld journal of transplantation2025
Outcomes of living donor kidney transplantation from extended criteria donors to extended criteria recipients: A retrospective cohort study.
Article in World journal of transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
backgroundLiving donor kidney transplantation (LDKT) is considered the gold standard for treating end-stage kidney disease. Previous studies have highlighted the impact of donor and recipient demographics in influencing post-transplant outcomes. We believe that patient and graft outcomes in a tertiary university hospital setting will have no difference between pairs of standard criteria
aimTo investigate the outcomes of allocating EC donation (ECD) kidneys to EC recipients (ECR) in LDKT and compare them to standard and mixed standard and EC pair counterparts.
methodsWe collected data from adult LDKTs conducted between April 2017 and April 2022. Donor-recipient pairs were grouped based on criteria as follows: (1) Group 1: Standard criteria donor (SCD) to standard criteria recipient (SCR); (2) Group 2: SCD to ECR; (3) Group 3: ECD to SCR; and (4) Group 4: ECD to ECR.
resultsA total of 149 living donor transplants were analysed over a 5-year period. Graft survival, patient survival, and graft function were similar across all four groups. The incidence of common postoperative complications was as follows: (1) Perioperative bleeding (5.6%); (2) Surgical site infection (6.8%); and (3) Incisional hernia (7.4%). No statistically significant differences were found in patient or graft outcomes amongst the four groups. Multivariate analysis showed that group 4 recipients might experience inferior 5-year graft function (
conclusionIn LDKT, long-term patient and graft outcomes are comparable amongst different combinations of standard
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