ArticleSleep advances : a journal of the Sleep Research Society2025
Bedtime regularization as a potential adjunct therapy for hypertension: a proof-of-concept study.
Article in Sleep advances : a journal of the Sleep Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Nocturnal peak in cardiac baroreflex effectiveness aligns with nocturnal trough in systolic blood pressure in young healthy adults: Possible circadian effects.Physiological reports · 2026Article
- Fluctuations in Sleep Duration and Timing and Cardiometabolic Risk.Arteriosclerosis, thrombosis, and vascular biology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Study Objectives: Sleep irregularity is associated with elevated blood pressure (BP). Whether sleep regularity decreases BP is not known. We hypothesized that an intervention involving 2 weeks of sleep regularization would decrease BP in people with hypertension. Methods: Eleven people with hypertension (four males/seven females, age: mean 53 [range 45-62 years]), body mass index (32 ± 6 kg/m Results: Bedtime variability (32.4 ± Conclusions: In this proof-of-concept study, 2 weeks of bedtime regularization decreased 24-h and nighttime BP in people with hypertension, suggesting that this may be a simple, yet low-risk, adjunctive strategy to control BP in many people with hypertension. This ought to be tested in a larger randomized controlled trial.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.