ReviewJournal of food allergy2025
Food protein-induced enterocolitis syndrome: Disease burden for patients and families.
Review in Journal of food allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Non IgE-mediated food allergy: Current knowledge and unmet needs.Journal of food allergy · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The impact of food protein-induced enterocolitis syndrome (FPIES) extends beyond the direct effects after consumption of an inciting food. Although elimination of the trigger food does alleviate the symptoms of FPIES, it does not address the burden of disease among patients and families living with FPIES. When managing FPIES, consideration should be taken with regard to the potential impact and complications attributed to food avoidance. Objective: The objective was to review the epidemiology of FPIES and discuss the associated complications of FPIES, such as nutritional deficiencies, food aversions, financial burden, and overall effect on quality of life of patients and families with FPIES. Methods: A literature review was conducted through the aid of the University of Southern California Norris Medical Library services. Only peer-reviewed sources were used. Results: The incidence of FPIES ranges from 0.0041 to 0.7%. When compared with individuals with immunoglobulin E (IgE) meditated food allergies, caregivers of children with FPIES reported poor quality of life and increased feeding difficulties. Individuals with multiple trigger foods are more likely to develop food aversion compared with individuals with one food trigger. Failure to thrive, poor weight gain, and nutritional deficiencies can be seen because of food restriction in patients with FPIES and do not just represent presenting symptoms of FPIES. Conclusion: There was poorer quality of life and increased psychosocial burden among individuals with FPIES and caregivers of individuals with FPIES. Given the associated complications of nutritional deficiency, feeding difficulties, food aversion, and psychosocial stress, FPIES management should involve a multidisciplinary approach that involves nutrition, speech therapy, occupational therapy, and/or mental health services. Further research and data are needed to assess the financial burden of disease on individuals and families affected by FPIES and the long-term impact that FPIES may have on the growth and nutrition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.